Associate Director, Quantitative Pharmacology & Pharmacometrics

Merck; West Point (PA); Hybrid; USD 180,000 - 260,000; Full time

Benefits offered by this job

Hybrid work arrangement

Job summary

Merck & Co., Inc. seeks an Associate Director in Quantitative Pharmacology to advance cardiometabolic pipelines. You will lead model-based strategies, translational PK/PD, and clinical trial simulations to inform decisions across discovery and development teams.

The role requires expertise in pharmacometrics, strong communication, and collaboration with internal and external partners, with hybrid work arrangements in Rahway, NJ or West Point, PA.

Qualifications

• Ph.D. or equivalent with 4+ years in drug development; PharmD with 6+ years; MS with 8+ years.
• Background in biopharmaceutics, pharmacometrics or related quantitative discipline.
• Experience with population PK/PKPD analyses using standard software (R/Matlab/Phoenix/NONMEM/Monolix).
• Strong communication and cross-disciplinary collaboration skills.
• Knowledge of modeling complex therapeutics, QSP preferred.

Responsibilities

• Develop model-based strategies, translational PK/PD, population PK/PD analyses and clinical trial simulations.
• Represent QP2 on cardiometabolic discovery and development teams to inform decisions.
• Collaborate with vendors and partners to align quantitative approaches for decision making.
• Contribute to study design, data interpretation, reporting, and regulatory submissions.
• Engage with regulatory expectations and defend modeling in submissions.

Skills

BI

Database Design

Data Engineering

Data Modeling

Data Science

Data Visualization

Machine Learning

Software Development

Stakeholder Management

Waterfall Model

Education

PhD

PharmD

MS

Tools

R

Matlab

Phoenix

NONMEM

Monolix

Job description

Merck & Co., Inc. seeks an Associate Director in Quantitative Pharmacology to advance cardiometabolic pipelines. You will lead model-based strategies, translational PK/PD, and clinical trial simulations to inform decisions across discovery and development teams.

The role requires expertise in pharmacometrics, strong communication, and collaboration with internal and external partners, with hybrid work arrangements in Rahway, NJ or West Point, PA.