Associate Director, Modeling & Simulation (Hybrid/Remote)

Viridian Therapeutics, Inc.; United States; Hybrid; USD 170,000 - 210,000; Full time

Benefits offered by this job

Stock options

Medical, dental, vision insurance

401(k) company match

Vacation and holidays

Job summary

Viridian Therapeutics, Inc. is seeking an Associate Director to lead hands-on Modeling and Simulation activities across Biometric Sciences. You will develop and refine modeling approaches for clinical trial design, apply Bayesian and ML methods, and support portfolio strategy.

The role offers hybrid work in Waltham, MA or fully remote with occasional HQ travel as needed. You will drive cross-functional analytical initiatives and build scalable data infrastructure to advance patient-focused

Qualifications

• Requires a PhD in statistics or biostatistics with 6+ years of relevant experience or an MS with 10+ years of relevant experience.
• Demonstrated expertise in statistical computing environments and infrastructure.
• Experience in clinical trial study design optimization through simulation methods.
• Expertise in modeling for portfolio decision-making and study design performance.

Responsibilities

• Build, manage, and analyze scalable clinical-trial data repositories supporting advanced modeling and simulations.
• Provide analytical support across Biometric Sciences and related departments (Pharmacology, Communications).
• Lead hands-on modeling projects including simulation, AI-enabled data review, and MIDD approaches.
• Develop and optimize biostatistical SOPs and templates and drive methodological innovation.
• Collaborate with external experts to strengthen scientific rigor and support innovation across the organization.
• Promote rapid, collaborative decision-making and ONE Team culture.

Skills

Statistical modeling

Clinical trial design

Bayesian methods

Joint modeling

Estimands

Adaptive design

Machine learning

Big data analysis

Education

PhD in statistics/biostatistics

MS in related field (with 10+ years of experience)

Tools

R

Python

HPC

Git

Job description

Viridian Therapeutics, Inc. is seeking an Associate Director to lead hands-on Modeling and Simulation activities across Biometric Sciences. You will develop and refine modeling approaches for clinical trial design, apply Bayesian and ML methods, and support portfolio strategy.

The role offers hybrid work in Waltham, MA or fully remote with occasional HQ travel as needed. You will drive cross-functional analytical initiatives and build scalable data infrastructure to advance patient-focused