Senior Modeling & Simulation Lead — Hybrid, High Impact

Vertex Pharmaceuticals LLC; Boston (MA); Hybrid; USD 168,000 - 252,000; Full time

Job summary

Vertex Pharmaceuticals is seeking a Modeling & Simulations Associate Director in Boston, MA to lead cross-functional drug development teams with state-of-the-art M&S methodologies. You will design and execute PK/PD analyses, clinical trial simulations and mechanism-based modeling to support critical development decisions.

The ideal candidate holds a Pharmacometrics-focused advanced degree with 6+ years (PhD) or 10+ years (Master's) in pharmacometrics applied to drug R&D, and has strong

Qualifications

• Master's or PhD in pharmaceutical sciences or related quantitative discipline with PKPD focus.
• PhD with 6 years or Master's with 10 years experience in pharmacometric applications in drug R&D.
• Experience in industry, academia or regulatory settings.

Responsibilities

• Lead cross-functional drug development teams on Modeling & Simulation plans and analyses.
• Develop and execute mechanism-based PK/PD analyses and population PK/PD analyses.
• Contribute to efficiency by evaluating new Modeling & Simulation tools and supporting training.

Skills

Population PK

PKPD modeling

Clinical trial simulations

Leadership

Collaborative skills

Communication

Drug development

Education

Pharmacometrics-focused advanced degree

Quantitative discipline

Tools

NonMem

PsN

R

Phoenix

Job description

Vertex Pharmaceuticals is seeking a Modeling & Simulations Associate Director in Boston, MA to lead cross-functional drug development teams with state-of-the-art M&S methodologies. You will design and execute PK/PD analyses, clinical trial simulations and mechanism-based modeling to support critical development decisions.

The ideal candidate holds a Pharmacometrics-focused advanced degree with 6+ years (PhD) or 10+ years (Master's) in pharmacometrics applied to drug R&D, and has strong