Associate Director, Data Science - Oncology & Omics AI

Merck

Boston (MA)

Hybrid

USD 160,000 - 251,000

Full time

5 days ago
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Benefits offered by this job

Hybrid work model

Job summary

Merck's Translational Genome Analytics team in Boston is seeking an Associate Director of Data Science to lead computational oncology projects. You will analyze bulk RNA-seq, WES/WGS, scRNA-seq and functional genomics screens to uncover cancer biology and nominate targets and biomarkers.

Collaboration across AI, ML, biology and software teams is essential. The role emphasizes rigorous statistics, multi-omics integration and deployment of AI tools to accelerate discovery, with travel up to 10%

Qualifications

  • PhD in a quantitative STEM field with 4+ years of relevant experience.
  • Deep experience analyzing large-scale NGS datasets (bulk RNA-seq, WES/WGS, scRNA-seq).
  • Strong statistics foundation and ML experience with biological data.
  • Proficiency in R or Python, Git, and Linux; cloud/data platform experience.

Responsibilities

  • Analyze large-scale oncology datasets to understand disease biology and drug action.
  • Analyze functional genomics screens to establish targets and mechanisms.
  • Nominate and prioritize drug combinations using multi-omics data.
  • Apply network-based and ML approaches to integrate data into coherent conclusions.
  • Collaborate across disciplines to enable reproducible, well-documented research.

Skills

R/Python
NGS data analysis
Statistics & ML
Cloud platforms
Collaboration & communication

Education

PhD in computational biology / related STEM

Tools

Nextflow
Databricks
AWS (S3)
Posit
Git
Linux

Job description

Merck's Translational Genome Analytics team in Boston is seeking an Associate Director of Data Science to lead computational oncology projects. You will analyze bulk RNA-seq, WES/WGS, scRNA-seq and functional genomics screens to uncover cancer biology and nominate targets and biomarkers.

Collaboration across AI, ML, biology and software teams is essential. The role emphasizes rigorous statistics, multi-omics integration and deployment of AI tools to accelerate discovery, with travel up to 10%

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