Analytical Scientist -- NEGDC6166691

Compunnel Inc.; St. Louis (MO); On-site; USD 65,000 - 90,000; Full time

Job summary

Compunnel Inc. in St. Louis seeks a Scientist II to join our Analytical R&D Department at the Life Sciences R&D facility.

You will contribute to high-level analytical support for product development scientists across R&D, manufacturing, and project teams. Key duties include performing LC-MS analyses for protein identification and quantification, operating high-resolution and triple quadrupole LC-MS systems, and preparing samples with enzymatic and chemical methods while maintaining accurate

Qualifications

• Bachelor's degree in chemistry or related field.
• 2–5 years of relevant industry experience.
• Hands-on Mass Spectrometry (LC-MS) experience with high-resolution or triple quadrupole systems.
• Ability to work independently in a laboratory.

Responsibilities

• Perform LC-MS analysis for protein identification and quantification.
• Operate advanced mass spectrometry instruments (HRMS and QqQ).
• Prepare samples using enzymatic and chemical methods.
• Maintain accurate lab records and follow established laboratory procedures.
• Collaborate with R&D and cross-functional teams.

Skills

LC-MS analysis

Mass spectrometry

HPLC analysis

Lab teamwork

Education

Bachelor's degree in chemistry or related field

Tools

LC-MS platforms

HPLC instruments

Chromatographic software

Job description

The Scientist II will join the Analytical R&D Department at our Life Sciences R&D facility in St. Louis. In this role, you will be part of an active, multidisciplinary group of scientists dedicated to providing high level analytical support to product development scientists in R&D, manufacturing groups, and special project teams.

Key Responsibilities

• Perform LC-MS analysis for protein identification and quantification in complex samples.
• Operate advanced Mass Spectrometry instruments, including High-Resolution and Triple Quadrupole LC-MS.
• Prepare laboratory samples using enzymatic and chemical methods, including digestion, enrichment, depletion, and labeling.
• Prepare reagents, perform pipetting, and conduct sample preparation and laboratory experiments.
• Characterize large biomolecules, including monoclonal antibodies, multispecific antibodies, and antibody-drug conjugates (ADCs).
• Perform HPLC analysis and utilize chromatographic software for data analysis.
• Maintain accurate laboratory records and follow established laboratory procedures.
• Work independently while collaborating with R&D scientists and cross-functional teams.

Minimum Qualifications

• Bachelor's degree in chemistry or a related scientific field.
• 2–5 years of relevant industry experience.
• Hands-on experience with Mass Spectrometry (LC-MS).
• Experience with High-Resolution or Triple Quadrupole LC-MS platforms.
• Knowledge of enzymatic and chemical sample preparation techniques.
• Ability to work independently in a laboratory environment.