Analytical QC Scientist I (Gene Therapy)

Forge Biologics; Columbus (OH); On-site; USD 90,000 - 120,000; Full time

Benefits offered by this job

Health insurance starting day one

Paid time off

401(k) with company match

Onsite fitness facility

Job summary

Forge Biologics in Columbus, OH is seeking a Scientist I, Quality Control (Analytical) to lead analytical method execution, validation, and troubleshooting for AAV vectors, plasmids, and cell banks. You will act as SME for nucleic acid-, protein-, or cell-based assays, drive novel method development, and mentor junior staff.

The role emphasizes cGMP-compliant workflows, collaboration with Analytical Development, and contributing to QC documentation and regulatory readiness.

Qualifications

• Bachelor's, Master's, or PhD in a relevant scientific field (e.g., biology, biochemistry, molecular biology). Advanced degree preferred.
• Familiar with analytical methods and QA/QC principles.
• Experience in cGMP environments is desirable.

Responsibilities

• Perform in-process, release, and stability testing for viral vector/gene therapy products, plasmids, and cell banks.
• Function as an SME for nucleic acid-based, protein-based, or cell-based assays and related QC methods.
• Support troubleshooting as SME and represent QC during audits and inspections.
• Ensure qualifications, validations, and transfer of analytical methods to QC in a phase-appropriate fashion.

Skills

Analytical skills

Mentoring

Quality control

Troubleshooting

Data interpretation

cGMP knowledge

Education

Bachelor's degree

Master's degree

PhD

Tools

EQMS

LIMS

Job description

Forge Biologics in Columbus, OH is seeking a Scientist I, Quality Control (Analytical) to lead analytical method execution, validation, and troubleshooting for AAV vectors, plasmids, and cell banks. You will act as SME for nucleic acid-, protein-, or cell-based assays, drive novel method development, and mentor junior staff.

The role emphasizes cGMP-compliant workflows, collaboration with Analytical Development, and contributing to QC documentation and regulatory readiness.