Analytical Development Scientist I – Flow & Cell Assays

Legend Biotech US; New Jersey; On-site; USD 96,000 - 126,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k) with company match

Parental leave

Job summary

Legend Biotech US is seeking a Scientist I, Analytical Development in Somerset, NJ to join the Research and Development team. You will establish, develop, and qualify analytical methods to support cell therapy programs, including flow cytometry, cell‑based potency, and immunoassays for product characterization and release.

You will author methods, maintain notebooks, and collaborate with PD, QC, and Manufacturing to ensure timely method transfers and adherence to ALCOA+ standards.

Qualifications

• Bachelor’s degree in related field with 5+ years experience, or Master’s 3–5 years, or PhD 0–2 years.
• Experience in flow cytometry, mammalian cell culture, ELISA and cell-based assays.
• Experience with compendial methods preferred.
• Lentiviral vector characterization including infectious titer, potency, transduction.
• Strong ICH knowledge for method qualification.
• Experience with assay qualification, release testing, and product characterization.
• Experience with SOPs and document review workflows.
• Detail-oriented with strong problem‑solving and decision‑making.
• Excellent written and verbal communication skills; English; Mandarin preferred.
• Proficiency with GraphPad Prism, PowerBI, JUMP, and R.

Responsibilities

• Develop, optimize, and execute analytical methods for viral vector and CAR‑T product characterization.
• Author and review methods, protocols, and reports.
• Maintain reagent inventory and procure materials as needed.
• Generate and qualify critical materials for analytical methods.
• Ensure laboratory safety standards (PPE, BSL2).
• Perform pre-qualification, assay qualification, release, and characterization testing.
• Transfer methods to QC and collaborators.
• Maintain electronic lab records per ALCOA+ standards.
• Conduct peer reviews and data integrity checks.
• Collaborate cross-functionally with PD, QC, and Manufacturing.
• Present data at internal and external forums; balance multiple projects.

Skills

Flow cytometry

Mammalian cell culture

ELISA

Cell-based assays

SOPs & document review

Problem solving

Verbal & written communication

GraphPad Prism

PowerBI

JUMP

R

Education

Bachelor’s degree in a related field

Master’s degree

PhD

Tools

GraphPad Prism

PowerBI

JUMP

R

Job description

Legend Biotech US is seeking a Scientist I, Analytical Development in Somerset, NJ to join the Research and Development team. You will establish, develop, and qualify analytical methods to support cell therapy programs, including flow cytometry, cell‑based potency, and immunoassays for product characterization and release.

You will author methods, maintain notebooks, and collaborate with PD, QC, and Manufacturing to ensure timely method transfers and adherence to ALCOA+ standards.