Analytical Development Lead for Peptides & Oligos

Scorpion Therapeutics; Boston (MA); Hybrid; USD 180,000 - 240,000; Full time

Job summary

Scorpion Therapeutics seeks an Associate Director, Analytical Development to lead in-house lab operations supporting neuromuscular disorder therapies in our pipeline.

Responsibilities include developing and validating analytical methods for peptides, oligonucleotides, and conjugates; overseeing impurity profiling and CQA assessments; and guiding regulatory documentation and interactions with external contract labs. The role emphasizes cross-functional leadership and team mentorship.

Qualifications

• PhD in Chemistry or related field with 5+ years’ experience (PhD) or 8+ years (Master’s).
• Expertise in peptides, oligonucleotides and conjugates.
• Proven leadership in CQA and regulatory submissions.

Responsibilities

• Manage and optimize analytical methods development and validation for peptides, oligos, and conjugates.
• Oversee characterization activities, impurity profiling, and CQA assessments.
• Lead extended characterization, comparability strategies, and regulatory documentation.
• Manage external contract labs.
• Mentor team members and foster cross-functional collaboration.

Skills

Peptides

Oligonucleotides

Conjugates

Analytical method development

Education

PhD in Chemistry or related field

Master’s degree in Chemistry or related field

Tools

UHPLC-TOF

UHPLC-MS/MS

Job description

Scorpion Therapeutics seeks an Associate Director, Analytical Development to lead in-house lab operations supporting neuromuscular disorder therapies in our pipeline.

Responsibilities include developing and validating analytical methods for peptides, oligonucleotides, and conjugates; overseeing impurity profiling and CQA assessments; and guiding regulatory documentation and interactions with external contract labs. The role emphasizes cross-functional leadership and team mentorship.