Analytical Development Lead for Next-Gen Biotech

Nūmi; Paris (TX); On-site; USD 101,000 - 145,000; Full time

Benefits offered by this job

Competitive salary

ESOP

Partial health insurance coverage

Transportation stipend

Lunch coverage

Employee wellbeing emphasis

Job summary

Nūmi is an early-stage biotech in Paris building a platform for human milk constituents. We seek an Analytical Development Lead to characterise our ingredients with hands-on LC-MS/HPLC methods and to build the analytical platform for pilot and regulatory batches.

You will define what to measure, how to measure it, and ensure data reliability, collaborating with Process Development, Reg & QC, and external CROs. This senior role offers growth, ESOP, and competitive compensation.

Qualifications

• PhD or MSc with extensive industry experience in analytical development for food ingredients, infant nutrition or biologics.
• Hands-on track record characterising complex ingredients (proteins, oligosaccharides or lipids).
• Experience developing and validating analytical methods with LC-MS, HPLC/UPLC and related techniques.
• Quality-controlled lab experience (GLP or ISO 17025).
• Experience working with external analytical labs or CROs.
• Excellent written and spoken English; French is a plus.

Responsibilities

• Define and deliver the analytical strategy across the ingredient portfolio from R&D to pilot and regulatory batches.
• Build the full characterisation package: identity, purity, composition, impurities.
• Benchmark ingredients against human milk counterparts and references.
• Characterise process-related impurities from cell culture (host proteins, DNA, media components).
• Develop, optimise, and qualify fit-for-purpose methods (LC-MS, LC-MS/MS, HPLC/UPLC, etc.)
• Transfer methods to QC or partner labs and set up SOPs and documentation.
• Provide fast in-process and release analytics to upstream/downstream teams.
• Design stability and batch-to-batch comparability studies.
• Collaborate with Reg & QC, Data teams, and external partners; manage CROs.
• Evaluate new analytical technologies and AI-enabled tools.

Skills

Analytical development

Method development

English communication

CRO collaboration

Regulatory dossiers

Quality systems

Project management

Education

PhD in analytical chemistry

MSc in related discipline

Tools

LC-MS

LC-MS/MS

HPLC/UPLC

HPAEC-PAD

SDS-PAGE

Western blot

ELISA

Job description

Nūmi is an early-stage biotech in Paris building a platform for human milk constituents. We seek an Analytical Development Lead to characterise our ingredients with hands-on LC-MS/HPLC methods and to build the analytical platform for pilot and regulatory batches.

You will define what to measure, how to measure it, and ensure data reliability, collaborating with Process Development, Reg & QC, and external CROs. This senior role offers growth, ESOP, and competitive compensation.