Analytical Chemist I — LC-MS/ADME Focus (CRO)

Eurofins; Saint Charles (MO); On-site; USD 68,000 - 95,000; Full time

Benefits offered by this job

Medical, dental, vision benefits

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA Discovery Services is seeking a Scientist I – Analytical Chemist in St. Charles, MO to support contract research services. The role requires hands-on LC-MS/LC-UV experience and a strong background in ADME/DMPK methods within a CRO or industry lab.

The ideal candidate will have a B.S./M.S./Ph.D. with relevant lab experience and a proven track record in method development, validation, and data integrity in a GxP environment.

Qualifications

• Direct experience with LC-MS and/or LC-UV in CRO or industry lab for ADME/DMPK applications.
• Experience in a Quality Management System.
• Mass spectrometry-based quantification for ADME/DMPK in biological matrices.
• Experience with analytical method development and optimization.
• Knowledge of validation of bioanalytical methods per FDA/ICH guidelines.
• Experience with liquid handling, automation, SPE, HTS and large-scale screening.
• Experience in leading small teams and managing projects.
• Experience delivering results in R&D or innovation programs.
• Authorization to work in the United States indefinitely without sponsorship.

Responsibilities

• Performs laboratory work meeting the physical job requirements.
• Develops LC-MS methods for ADME/DMPK applications.
• Maintains and troubleshoots mass spectrometers and HPLC units (Sciex/Waters a plus).
• Prepares and manages buffers, reagents, semi-finished and finished goods.
• Provides solutions to complex problems and initiates process improvements.
• Maintains high data quality and reproducibility.
• Performs data and report QC review and may support study director.
• Takes ownership of client projects with minimal supervision.
• Supports validation of new methods and expansion of service lines.
• Complies with GxP site requirements and safety training.

Skills

LC-MS / LC-UV experience

Quality Management System

Mass spectrometry quantification

Method development

Bioanalytical method validation

Liquid handling & automation

SPE / HTS

Leadership & project management

R&D project leadership

US work authorization

Education

B.S. with minimum 5 years relevant laboratory experience

M.S. with minimum 3 years relevant laboratory experience

Ph.D. with minimum 1 year relevant laboratory experience

Tools

LC-MS instruments

HPLC

Sciex instruments

Waters instruments

Job description

Eurofins USA Discovery Services is seeking a Scientist I – Analytical Chemist in St. Charles, MO to support contract research services. The role requires hands-on LC-MS/LC-UV experience and a strong background in ADME/DMPK methods within a CRO or industry lab.

The ideal candidate will have a B.S./M.S./Ph.D. with relevant lab experience and a proven track record in method development, validation, and data integrity in a GxP environment.