Process Engineer: Scale-Up & Process Optimization

GlaxoSmithKline Pte Ltd; Singapore; On-site; SGD 70,000 - 110,000; Full time

Job summary

GlaxoSmithKline Pte Ltd is seeking a process engineer to design, improve and support manufacturing processes at our Singapore site. You will collaborate with operations, quality, engineering and safety teams to solve problems, deliver projects and improve site performance.

You will lead process engineering activities for NCE projects, troubleshoot issues, support scale-up and tech transfer, and help implement new equipment and computer system qualification/validation.

Qualifications

• Bachelor’s degree in chemical, biochemical or related engineering field.
• Minimum 2 years’ experience in manufacturing or process engineering in pharmaceutical, biotech or related industry.
• Practical experience with process troubleshooting and root cause analysis.
• Experience supporting equipment and computer system commissioning, qualification or validation.
• Knowledge of current Good Manufacturing Practice (cGMP), health and safety requirements. Conduct hazard assessments, complete Process Risk Assessments, review batch records, and prepare documentation such as Work Instructions (WIs) or Standard Operating Procedures (SOPs).
• Strong communication and teamwork skills with a commitment to clear, respectful collaboration.

Responsibilities

• Lead process engineering activities for NCE projects in the pilot plant, collaborating with Chemists, Operations, and Engineering teams to review scale-up requests and identify optimum plant configurations for efficient process transitioning.
• Troubleshoot process and equipment issues to restore and improve production reliability.
• Support process development and optimization to scale-up or tech transfer processes.
• Define and monitor key performance indicators and drive improvement actions with stakeholders.
• Support new equipment and computer system installation, commissioning, qualification and validation activities.
• Contribute to facility capital projects.
• Provide technical guidance and training to operators and colleagues to embed best practices.

Skills

Process Engineering

Troubleshooting

Root Cause Analysis

GMP Knowledge

Team Collaboration

Education

Bachelor’s degree in chemical, biochemical or related engineering

Tools

Equipment Commissioning

Computer System Validation

Job description

GlaxoSmithKline Pte Ltd is seeking a process engineer to design, improve and support manufacturing processes at our Singapore site. You will collaborate with operations, quality, engineering and safety teams to solve problems, deliver projects and improve site performance.

You will lead process engineering activities for NCE projects, troubleshoot issues, support scale-up and tech transfer, and help implement new equipment and computer system qualification/validation.