Bioprocess Operator (Fermentation)

ScienTec Consulting Pte. Ltd.; Singapore; On-site; SGD 42,000 - 78,000; Full time

Job summary

Scien Tec Consulting Pte. Ltd. is recruiting for an Upstream/Downstream Bioprocess Operator in Singapore.

The role involves operating bioreactors (10L–100L), downstream equipment, and in-process testing to ensure production targets and product quality are consistently met. The candidate should have a Diploma or equivalent in Food Science/Technology or related fields, with 5+ years in food manufacturing or fermentation and familiarity with GMP/GDP and ISO/FB certifications.

Qualifications

• Diploma or equivalent in Food Science/Technology, Biotechnology, Bioengineering, Chemical Engineering, or a related field.
• Minimum 5 years of experience in food manufacturing or a related field; fermentation experience is a strong advantage.
• Knowledge of GMP and GDP.
• Familiarity with ISO22000, FSSC22000, or BRC certification advantageous.

Responsibilities

• Operate both upstream and downstream production processes including fermentation, centrifugation, filtration, and chromatography.
• Perform in-process testing and ensure quality targets are met according to GMP/GDP standards.
• Maintain documentation such as Batch Manufacturing Records and maintenance/calibration records.
• Monitor and control processes via on-site panels and SCADA/Controls systems; report issues and liaise with vendors.

Education

Diploma or equivalent in Food Science/Technology, Biotechnology, Bioengineering, Chemical Engineering, or a related field

Job description

About the Role

You’ll operate bioreactors at multiple scales, run downstream processes including chromatography, spray drying, filtration, and centrifugation, and conduct in-process testing to ensure production targets and product quality are consistently met.

What You Will Do

Upstream Operations

• Perform material handling including receiving, storage, and dispensing
• Operate fermentation processes including media preparations, sampling, adjustments, and charge out for plate, shake flask, 10L, and 100L bioreactors

Downstream Operations

• Operate batch/continuous centrifuge, decanter, high-pressure homogenisation, filtration, chromatography (including FPLC), spray drying, freeze drying, drum drying, solvent extraction, colloid mill, and filter press
• Perform CIP/SIP procedures as per SOP

In-Process Testing & Quality

• Conduct in-process testing including moisture analysis, pH, optical density, microscopy, dry/wet cell weight, SDS-PAGE, GC, and HPLC
• Complete all documentation (Batch Manufacturing Records, CIP, Maintenance, Calibration, and Cleaning Records) in accordance with GMP and GDP standards

Process Monitoring & Control

• Monitor and control processes via on-site panel and remotely through SCADA/Controls systems
• Monitor process trends and alarms; report plant utilities issues and liaise with vendors for recovery actions

Maintenance, Safety & Housekeeping

• Perform pre- and post-campaign activities, manual cleaning, and equipment inspection
• Perform basic maintenance of production equipment
• Conduct stock counts and generate shift reports; ensure proper shift handover communications
• Assist Process Engineers in troubleshooting deviations; report all actual, near-miss, and potential incidents
• Participate in 5S, lean manufacturing, and continuous improvement initiatives
• Assist in project commissioning and validation activities as required

What We Are Looking For

• Diploma or equivalent in Food Science/Technology, Biotechnology, Bioengineering, Chemical Engineering, or a related field
• Minimum 5 years of experience in food manufacturing or a related field; experience in fermentation is a strong advantage
• Knowledge of Good Manufacturing Practices (GMP) and Good Documentation Practices (GDP)
• Familiarity with food safety requirements; experience with ISO22000, FSSC22000, or BRC certification implementation is advantageous

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This authorizes us to:

• Contact you about potential opportunities.
• Delete personal data as it is not required at this application stage.

All applications will be processed with strict confidence. Only shortlisted candidates will be contacted.

Ho Kah Yeow | R1879233

ScienTec Consulting Pte Ltd |11C5781