Lab Manufacturing Production Operator

ScienTec Consulting Pte. Ltd.; Singapore; Presencial; SGD 60.000 - 90.000; Jornada completa

Descripción de la vacante

ScienTec Consulting Pte. Ltd. is seeking an experienced bioprocess technician to operate bioreactors and manage downstream steps from fermentation to spray drying.

You will run chromatography, filtration, and related unit operations, and perform in-process testing to ensure product quality. Responsibilities include batch handling, maintaining GMP/GDP documentation, and supporting 5S and continuous improvement initiatives.

Formación

• Diploma or equivalent in Food Science/Technology, Biotechnology, Bioengineering, Chemical Engineering, or related field.
• Minimum 5 years of experience in food manufacturing or related field; fermentation experience is a strong advantage.
• Knowledge of Good Manufacturing Practices (GMP) and Good Documentation Practices (GDP).
• Familiarity with food safety requirements; ISO22000, FSSC22000, or BRC certification implementations advantageous.

Responsabilidades

• Operate bioreactors across scales (10L to 100L) and perform upstream operations.
• Operate downstream processes including centrifugation, filtration, chromatography, spray drying, and related unit operations.
• Conduct in-process testing (moisture, pH, OD, SDS-PAGE, GC, HPLC) and maintain Batch Manufacturing Records and related documentation per GMP/GDP.
• Monitor processes via SCADA/Controls systems and liaise with vendors for recovery actions.
• Participate in 5S, lean manufacturing, and continuous improvement initiatives; assist in commissioning and validation activities.

Conocimientos

GMP knowledge

GDP knowledge

5S

Lean manufacturing

Documentation discipline

SOP adherence

Educación

Diploma or equivalent in Food Science/Technology, Biotechnology, Bioengineering, Chemical Engineering, or related field

Herramientas

SCADA/Controls systems

FPLC

HPLC

GC

SDS-PAGE

Descripción del empleo

About the Role

You'll operate bioreactors at multiple scales, run downstream processes including chromatography, spray drying, filtration, and centrifugation, and conduct in-process testing to ensure production targets and product quality are consistently met.

What You Will Do

Upstream Operations

• Perform material handling including receiving, storage, and dispensing
• Operate fermentation processes including media preparations, sampling, adjustments, and charge out for plate, shake flask, 10L, and 100L bioreactors

Downstream Operations

• Operate batch/continuous centrifuge, decanter, high-pressure homogenisation, filtration, chromatography (including FPLC), spray drying, freeze drying, drum drying, solvent extraction, colloid mill, and filter press
• Perform CIP/SIP procedures as per SOP

In-Process Testing & Quality

• Conduct in-process testing including moisture analysis, pH, optical density, microscopy, dry/wet cell weight, SDS-PAGE, GC, and HPLC
• Complete all documentation (Batch Manufacturing Records, CIP, Maintenance, Calibration, and Cleaning Records) in accordance with GMP and GDP standards

Process Monitoring & Control

• Monitor and control processes via on-site panel and remotely through SCADA/Controls systems
• Monitor process trends and alarms; report plant utilities issues and liaise with vendors for recovery actions

Maintenance, Safety & Housekeeping

• Perform pre- and post-campaign activities, manual cleaning, and equipment inspection
• Perform basic maintenance of production equipment
• Conduct stock counts and generate shift reports; ensure proper shift handover communications
• Assist Process Engineers in troubleshooting deviations; report all actual, near-miss, and potential incidents
• Participate in 5S, lean manufacturing, and continuous improvement initiatives
• Assist in project commissioning and validation activities as required

What We Are Looking For

• Diploma or equivalent in Food Science/Technology, Biotechnology, Bioengineering, Chemical Engineering, or a related field
• Minimum 5 years of experience in food manufacturing or a related field; experience in fermentation is a strong advantage
• Knowledge of Good Manufacturing Practices (GMP) and Good Documentation Practices (GDP)
• Familiarity with food safety requirements; experience with ISO22000, FSSC22000, or BRC certification implementation is advantageous