ADC Biologics Manufacturing Specialist

AstraZeneca plc; Singapore; On-site; SGD 110,000 - 160,000; Full time

Job summary

AstraZeneca plc is building its first biologics campus in Singapore, delivering ADC capabilities across multiple units. As a Manufacturing Production Specialist, you will lead equipment qualification, startup activities, and shopfloor operations to ensure safe, compliant, and efficient manufacturing of life‑changing medicines.

You will collaborate with Engineering, Quality, MSAT, Validation, and EHS to support start-up, commissioning, and continuous improvement while advancing digital-enabled

Qualifications

• Bachelor’s degree in Engineering or related field.
• 5+ years of pharma or biopharma GMP manufacturing experience.
• Hands-on equipment troubleshooting, fault diagnosis, and issue resolution.
• Experience with equipment qualification and validation (FAT, SAT, IQ, OQ, PQ).
• Good GMP documentation, deviation management, change control, CAPA, and lifecycle management.
• Strong safety, quality, and delivery focus.
• Excellent written and verbal communication.
• Ability to work in startup environment.
• Cross-functional collaboration across Manufacturing, Engineering, Validation, QA, EHS.

Responsibilities

• Own assigned manufacturing unit equipment readiness and lifecycle.
• Lead start-up and qualification activities: FAT, SAT, commissioning, IQ/OQ/PQ.
• Provide shopfloor technical support and rapid troubleshooting.
• Drive SOPs, batch record inputs, line readiness, and training.
• Align DCS recipes and MES master batch records for audit readiness.
• Support deviations, CAPAs, change controls, and investigations.
• Collaborate across functions to progress qualification and production readiness.
• Lead New Product Introduction readiness and OEE improvements.
• Manage single-use systems and consumables inventory for continuity.
• Drive continuous improvement and reliability initiatives.

Skills

Equipment troubleshooting

Fault diagnosis

Issue resolution

GMP manufacturing

Communication skills

Team collaboration

Education

Bachelor’s degree in Eng/related field

Job description

AstraZeneca plc is building its first biologics campus in Singapore, delivering ADC capabilities across multiple units. As a Manufacturing Production Specialist, you will lead equipment qualification, startup activities, and shopfloor operations to ensure safe, compliant, and efficient manufacturing of life‑changing medicines.

You will collaborate with Engineering, Quality, MSAT, Validation, and EHS to support start-up, commissioning, and continuous improvement while advancing digital-enabled