Postdoc: Mechanobiology & Tendon-on-Chip Research

INL - International Iberian Nanotechnology Laboratory; Braga; Presencial; EUR 37 000 - 40 000; Tempo integral

Vantagens oferecidas por esta oferta de emprego

Private health insurance

Relocation support

30 working days annual leave

Diplomatic privileges

Resumo da oferta

The International Iberian Nanotechnology Laboratory (INL) in Braga, Portugal invites applications for a postdoctoral researcher to join the ERC FORTIFy project. The role centers on developing nanosystems that selectively interact with cellular mechanosensors and applying them to mechanobiology studies in tendon models.

You will culture iPSCs, build 3D tendon-on-chip systems, integrate imaging and omics data, and contribute to publications and grant writing.

Qualificações

• PhD in Cellular and Molecular Biology, Genetics, Bioengineering, Tissue Engineering or a closely related field.
• Extensive hands-on research experience in stem cell biology, mechanobiology, bioengineering, molecular/cellular biology, gene editing or related fields.
• Strong hands-on experience in culturing, maintaining and differentiating induced pluripotent stem cells (iPSCs).
• Experience with gene editing approaches for engineered cell lines.
• Experience with molecular biology techniques (qPCR, RT-PCR, Western blotting).
• Familiarity with genomic/transcriptomic technologies (RNA-seq, scRNA-seq).
• Experience with cell-based assays, immunofluorescence, and flow cytometry.

Responsabilidades

• Culture and manipulate primary and stem cells, particularly iPSCs, and assess responses by cellular and molecular biology techniques.
• Establish human iPSC-derived cell models, including 3D cultures, organoids and organ-on-chip for musculoskeletal disease research.
• Apply multimodal imaging, genomics and proteomics to investigate mechanobiological mechanisms.
• Plan and perform R&D activities, develop methods, analyze data and present results.
• Publish findings and present at international conferences; contribute to grant writing.
• Mentor graduate students and research assistants and coordinate group activities.

Conhecimentos

iPSC biology

Mechanobiology

Molecular biology

Gene editing

Flow cytometry

Immunofluorescence

3D cell culture

Organoid models

Formação académica

PhD in Cellular and Molecular Biology

Ferramentas

Benchling

SnapGene

Geneious

R

Python

Descrição da oferta de emprego

The International Iberian Nanotechnology Laboratory (INL) in Braga, Portugal invites applications for a postdoctoral researcher to join the ERC FORTIFy project. The role centers on developing nanosystems that selectively interact with cellular mechanosensors and applying them to mechanobiology studies in tendon models.

You will culture iPSCs, build 3D tendon-on-chip systems, integrate imaging and omics data, and contribute to publications and grant writing.