Senior Computational Chemist - Molecular Modeling

Placements24; Queenstown; Hybrid; NZD 140,000 - 210,000; Full time

Benefits offered by this job

Health insurance

Stock options

Home office stipend

Professional development

Job summary

Placements24 seeks a Senior Computational Chemist for a fully remote position based in New Zealand. Design and optimize computational workflows to guide drug discovery, collaborating with global teams to translate modeling results into experimental strategies.

The ideal candidate holds a PhD in Computational Chemistry or related field with 5+ years of industry experience and expertise in Schrödinger, MOE, and Discovery Studio, plus Python/Perl/Bash scripting.

Qualifications

• PhD required in Computational Chemistry, Cheminformatics, Theoretical Chemistry, or related field.
• Minimum 5 years of experience in computational chemistry, preferably in pharma/biotech.
• Proficiency with molecular modeling software and force fields.
• Programming skills in Python, Perl or Bash for data analysis.

Responsibilities

• Design and execute molecular modeling studies, including MD simulations and docking.
• Develop and apply QSAR models to predict properties and activities.
• Perform virtual screening of large compound libraries to identify candidates.
• Collaborate with medicinal chemists and biologists to translate findings into designs.
• Evaluate and implement new computational methods and software tools.
• Analyze complex data and generate actionable insights for experimental teams.
• Prepare reports, presentations, and publications.
• Stay updated with advancements in computational chemistry and related fields.
• Maintain and manage computational resources and databases.
• Contribute to patent portfolio through IP work.

Skills

Python

Perl

Bash

Education

PhD in Computational Chemistry or related field

Tools

Schrödinger Suite

MOE

Discovery Studio

Job description

About the Role

Our client, a pioneering force in drug discovery and development, is actively seeking a Senior Computational Chemist for a fully remote position. This is an exceptional opportunity to join a world-class research team and contribute to the design and optimization of novel therapeutic agents from your home office. You will leverage advanced computational chemistry techniques, including molecular modeling, QSAR, and virtual screening, to guide experimental efforts and accelerate the discovery process. The ideal candidate possesses a deep understanding of theoretical chemistry principles, extensive experience with computational chemistry software, and a proven ability to translate computational findings into practical applications. This remote role requires strong self-discipline, excellent communication skills for virtual collaboration, and a passion for making a significant impact on human health. We are committed to providing our remote scientists with the tools and support necessary to excel.

Key Responsibilities

• Design and execute molecular modeling studies, including molecular dynamics simulations and docking.
• Develop and apply quantitative structure-activity relationship (QSAR) models to predict compound properties and activities.
• Perform virtual screening of large compound libraries to identify potential drug candidates.
• Collaborate closely with medicinal chemists and biologists to integrate computational findings into drug design strategies.
• Evaluate and implement new computational chemistry methodologies and software tools.
• Analyze and interpret complex computational data, generating actionable insights for experimental teams.
• Prepare clear and concise reports, presentations, and scientific publications.
• Stay current with the latest advancements in computational chemistry, cheminformatics, and related fields.
• Maintain and manage computational resources and databases.
• Contribute to the intellectual property portfolio through patent applications.

Requirements

• Ph.D. in Computational Chemistry, Cheminformatics, Theoretical Chemistry, or a related field.
• Minimum of 5 years of experience in computational chemistry, preferably within the pharmaceutical or biotechnology industry.
• Expertise in molecular modeling software (e.g., Schrödinger Suite, MOE, Discovery Studio) and force fields.
• Proficiency in programming languages such as Python, Perl, or Bash for scripting and data analysis.
• Strong understanding of quantum mechanics, statistical mechanics, and physical organic chemistry.
• Experience with QSAR modeling and virtual screening techniques.
• Ability to work independently and manage multiple projects effectively in a remote environment.
• Excellent problem-solving, analytical, and critical thinking skills.
• Strong written and verbal communication skills for effective collaboration with global teams.
• Familiarity with databases and data management is beneficial.

Benefits

• Our client offers a highly competitive salary and a comprehensive benefits package, including robust health, dental, and vision insurance.
• Performance-based bonuses and stock options are part of the compensation.
• A generous annual stipend is provided for home office setup, professional development, and technology upgrades.
• Employees enjoy ample paid time off and flexible remote working hours.
• This role provides the unique opportunity to advance your career in computational chemistry while enjoying the benefits of a fully remote work-life balance.
• We are dedicated to fostering a supportive and innovative remote work culture.