PhD: Scalable Lipid Nanoparticle Purification & CFD

Delft University of Technology (TU Delft); Delft; On-site; EUR 37,000 - 47,000; Full time

Benefits offered by this job

Customisable compensation package

Discounts on health insurance

Monthly work costs contribution

Flexible work schedules

Job summary

Delft University of Technology invites applications for a PhD candidate in the SPARC program focused on purifying lipid-based drug delivery streams. You will design advanced filtration strategies, combine CFD modelling with experiments, and collaborate with industry partners Merck KGaA and Johnson & Johnson to validate novel purification approaches.

The role sits at Precision Therapeutics and involves cross-disciplinary work between Chemical Engineering and Process & Energy, with a 4-year

Qualifications

• MSc or equivalent in Chemical Engineering, Process Engineering, Mechanical Engineering, Nanotechnology or related field.
• Analytical mindset and ability to work across computational and experimental domains.
• Excellent communication skills in English and ability to work in a multidisciplinary team.
• Experience in CFD simulations or pharmaceutical downstream processes is a plus.

Responsibilities

• Computational modelling with CFD simulations to analyze flow, diffusion, and filtration in tangential flow filtration systems.
• Develop novel flow geometries balancing throughput and mechanical stress on lipid nanoparticles.
• Experimentally verify membranes and modularisation options for the purification train.

Skills

Analytical mindset

Interdisciplinary collaboration

Excellent English communication

CFD simulations

Education

MSc or equivalent in Chemical Engineering/Process Engineering/Mechanical Engineering/Nanotechnology

Tools

CFD software

Job description

Delft University of Technology invites applications for a PhD candidate in the SPARC program focused on purifying lipid-based drug delivery streams. You will design advanced filtration strategies, combine CFD modelling with experiments, and collaborate with industry partners Merck KGaA and Johnson & Johnson to validate novel purification approaches.

The role sits at Precision Therapeutics and involves cross-disciplinary work between Chemical Engineering and Process & Energy, with a 4-year