Postdoc in Cross-disciplinary Research in our 'Bio-microfluidics' Team

Delft University of Technology (TU Delft); Delft; On-site; EUR 42,000 - 62,000; Full time

Benefits offered by this job

Flexible working week

Excellent pension via ABP

232 leave hours per year (with option)

Job summary

The Post-doctoral researcher will join the bio-microfluidics team at TU Delft to develop a predictive lymphatic-on-a-chip platform for drug bioavailability studies. The project integrates a vascularized barrier and advanced 3D microfluidic systems to model absorption and lymphatic interactions, including applications for biologics and small molecules.

We seek candidates with a PhD and experience in microfluidics and cell culture, who are creative, team-oriented and proficient in English

Qualifications

• Ph.D. in a relevant field (as listed)
• Experience with microfluidics, fluorescence imaging, confocal imaging, micro-scale flow or mammalian cell culture highly desirable
• Creative, open-minded and proactive
• Excellent experimental and analytical skills
• Good team player
• Good English communication and writing skills.

Skills

microfluidics

fluorescence imaging

confocal imaging

micro-scale flow

mammalian cell culture

Education

PhD in a relevant field (e.g., chemical engineering, physics, electrical engineering, biophysics, bioengineering, materials science)

Job description

We are seeking a highly motivated Post-doc researcher with an interest in cross-disciplinary research to join our "bio-microfluidics team" at TU Delft.

Job description

1. Are you inspired by the potential to use microfluidics for cancer research?
2. Are you passionate to develop organ-on-a-chip for drug screening applications?
3. Would you thrive in a high-end, interdisciplinary research environment dedicated to drug bioavailability?

This project develops a predictive lymphatic on a chip platform to study and improve the subcutaneous bioavailability of therapeutics. The advanced 3D microfluidic system mimics human lymphatic transport and, for the first time, integrates a vascularized barrier to enhance physiological relevance. It enables mechanistic analysis of therapeutic absorption, distribution, and blood–lymphatic interactions, including applications for small molecules, viral vectors and CAR T therapies. The model will be validated using diverse biomolecules and optimized for evaluation of formulation, dosage, and microenvironmental factors. Ultimately, the platform aims to accelerate therapeutic development while reducing reliance on animal testing and improving translational predictability

The project is part of our TKI-PPS research project via close collaboration with phrama, which aims to develop a novel bioavailability-on-a-chip platform that addresses a critical unmet need in biologics development.

Job requirements

We are looking for candidates that meet the following criteria:

• Ph.D. degree in a relevant field such as chemical engineering, physics, electrical engineering, biophysics, bioengineering, materials science or similar;
• Prior experience with microfluidics, fluorescence imaging, confocal imaging, micro-scal flow or mammalian cell culture is highly desirable;
• Creative, open-minded and proactive;
• Excellent experimental and analytical skills;
• Good team player;
• Good English communication and writing skills.

TU Delft (Delft University of Technology)

Working at TU Delft means contributing to solutions that really make a difference.

For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow. These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future.

At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional. Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward.

Faculty Applied Sciences

With more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers.

Click here to go to the website of the Faculty of Applied Sciences.

Conditions of employment

• Duration of contract is 2 years. Temporary.
• A job of 38-40 hours per week.
• Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities.
• An excellent pension scheme via the ABP.
• The possibility to compile an individual employment package every year.
• Discount with health insurers on supplemental packages.
• Flexible working week.
• Every year, 232 leave hours (at 38 hours). You can also sell or buy additional leave hours via the individual choice budget.
• Plenty of opportunities for education, training and courses.
• Partially paid parental leave
• Attention for working healthy and energetically with the vitality program.

Will you need to relocate to the Netherlands for this job? TU Delft is committed to make your move as smooth as possible! The HR unit, Coming to Delft Service, offers information on their website to help you prepare your relocation. In addition, Coming to Delft Service organises events to help you settle in the Netherlands, and expand your (social) network in Delft. A Dual Career Programme is available, to support your accompanying partner with their job search in the Netherlands. .

Additional information

If you would like more information about this vacancy or the selection procedure, please contact Dr. Pouyan E. Boukany, via [e-mail].