PhD: Cell Therapy for Hereditary Eye Disease — Preclinical Models

Amsterdam UMC; Amsterdam; Presencial; EUR 36.000 - 45.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

End-of-year bonus

Public transport reimbursement

Bike scheme

BeFrank pension

Descripción de la vacante

Amsterdam UMC Research BV is offering a PhD-track position to develop, characterize and apply patient-based preclinical models, collaborating with researchers from Human genetics and clinicians from Emma Children's Hospital and Ophthalmology to translate clinical questions into experiments and interpret results for disease mechanisms and potential treatments.

You will culture patient-derived stem cells, optimize retinal differentiation, study in vitro and in vivo models, and integrate findings

Formación

• Master's degree in biomedical sciences or related field.
• Practical experience in experimental laboratory research and cell culture.
• Interest in disease models and genetic variation relationships.
• Willingness to work with in vivo models and training.
• Good English communication; Dutch is an advantage.

Responsabilidades

• Culture patient-derived stem cells and optimize retinal cell/tissue models.
• Characterize in vitro models at molecular, cellular and functional levels.
• Develop and characterize patient-based in vivo models and outcome measures.
• Apply models to investigate cell therapy and biomaterials with preclinical transplantations.
• Integrate findings with genetic and clinical patient data.
• Present results at Lifelong VISION, Emma CPM and scientific meetings; contribute to publications and PhD thesis.

Conocimientos

Experimental lab research

Cell culture

Stem cells

Differentiation protocols

English communication

Team collaboration

Educación

Master's degree in biomedical sciences or related field

Article 9 qualification (advantage)

Descripción del empleo

Amsterdam UMC Research BV is offering a PhD-track position to develop, characterize and apply patient-based preclinical models, collaborating with researchers from Human genetics and clinicians from Emma Children's Hospital and Ophthalmology to translate clinical questions into experiments and interpret results for disease mechanisms and potential treatments.

You will culture patient-derived stem cells, optimize retinal differentiation, study in vitro and in vivo models, and integrate findings