PhD Opportunity: Liver Biology, Organoids & CRISPR

Prinses Máxima Centrum; Netherlands; On-site; EUR 28,000 - 36,000; Full time

Job summary

The Prinses Máxima Centrum invites applications for a highly motivated PhD candidate to study human liver function and disease using in vitro organoid models and mechanistic studies. You will apply CRISPR-Cas tools, omics readouts, and advanced imaging within a collaborative group.

The 4-year project is hosted in an international lab focused on pediatric oncology, with English as the working language and a strong emphasis on multidisciplinary training and scientific excellence.

Qualifications

• MSc completed in a biology related field or equivalent
• Strong background in molecular/cellular biology and stem cell biology
• Experience with internships in competitive institutions preferred
• Bioinformatic or imaging experience is a plus

Responsibilities

• Develop human liver in vitro models to study function and disease
• Work with organoids, CRISPR-Cas, and omics readouts to investigate metabolism
• Conduct mechanistic experiments and generate publishable data
• Collaborate in an international, multidisciplinary research environment

Skills

Molecular biology

Cell biology

Stem cell biology

Independent work

Education

MSc in relevant field

Tools

Bioinformatics tools

Advanced imaging tools

Organoid culture

Job description

The Prinses Máxima Centrum invites applications for a highly motivated PhD candidate to study human liver function and disease using in vitro organoid models and mechanistic studies. You will apply CRISPR-Cas tools, omics readouts, and advanced imaging within a collaborative group.

The 4-year project is hosted in an international lab focused on pediatric oncology, with English as the working language and a strong emphasis on multidisciplinary training and scientific excellence.