PhD Candidate: Brain BBB Organoids & Nanocarrier Delivery

Komwerkeninzorgenwelzijn; Amsterdam; On-site; EUR 36,000 - 45,000; Full time

Benefits offered by this job

Public transport reimbursement

BeFrank pension

Bike scheme

End-of-year bonus

Job summary

Amsterdam UMC Research BV invites a highly motivated researcher to join a public-private partnership exploring drug delivery across the blood-brain barrier using hiPSC-derived cortical organoids. You will compare natural and synthetic nanocarriers and study neurovascular interactions in disease modelling and drug screening.

The position starts November 1st 2026; contract for 12 months with potential extension up to four years.

Qualifications

• Master’s degree in neuroscience, biomedical sciences or related field.
• Experience with hiPSC culture and differentiation, BBB models or brain organoids.
• Excellent written and spoken English; ability to work independently and in teams.
• Familiarity with organ-on-chip or nanoparticle technologies an advantage.

Responsibilities

• Develop and apply advanced human in vitro models to study drug delivery across the BBB.
• Compare natural and synthetic nanocarriers for brain delivery.
• Work with hiPSC-derived cortical organoids and BBB models.
• Investigate neurovascular interactions and therapeutic delivery to the brain.
• Contribute to disease modelling, target discovery and drug screening.
• Collaborate with Amsterdam UMC and Locsense within a public-private partnership.

Skills

English skills

Independent work

Education

Master’s degree in neuroscience, biomedical sciences or related field

Tools

hiPSC culture and differentiation

Blood-brain barrier models

Organ-on-chip

MEA or nanoparticle technologies

Job description

Amsterdam UMC Research BV invites a highly motivated researcher to join a public-private partnership exploring drug delivery across the blood-brain barrier using hiPSC-derived cortical organoids. You will compare natural and synthetic nanocarriers and study neurovascular interactions in disease modelling and drug screening.

The position starts November 1st 2026; contract for 12 months with potential extension up to four years.