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KLK OLEO in Malaysia's Klang Bukit Raja R&D centre is seeking a Researcher II to synthesize compounds, optimize routes, and support lead optimization.
You will purify multi-step products, document procedures, and collaborate with international teams, applying NMR and preparative chromatography.
Ph.D. or Master in Chemistry with 5+ years in synthetic organic chemistry; capable of designing scalable processes for commercial production.
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THIS POSITION WILL BE BASED IN R&D CENTRE AT BUKIT RAJA, KLANG, SELANGOR.
ROLE AND RESPONSIBILITIES
Synthesize compounds of interest in support of lead optimization, discovery and development programs.
Develop and optimize synthetic methods to synthesize compounds.
Purify the products of multiple-step syntheses on milligram to gram reaction scales.
Meet on periodical basis with key administrative and technical staff to receive project update & troubleshoot technical issues.
Prepare status reports as well as detailed reports on the procedures, protocols, and experimental data in a suitable format for publication in relevant scientific journals and/or patent disclosure if applicable.
Support any laboratory activities, to include general upkeep as well as chemical storage and movement and equipment usage and maintenance.
Assist the project teams as needed with all aspects of the synthesis, purification and characterization of compounds and execute administrative tasks in support of the efforts detailed in this task.
JOB SUCCESS REQUIREMENTS
Ph.D. or Master in Chemistry with minimum 5 years of relevant industry or academic experiences in synthetic organic chemistry.
Life sciences graduate will not be considered.
Excellent hands‑on working knowledge and understanding of chemical reaction monitoring (and relevant techniques), reaction work up, product isolation techniques and purification techniques.
Experience in multi‑step synthesis of complex molecules with ability to design and develop synthesis methodology (e.g. esterification, enzymatic esterification, interesterification etc.) and practical synthetic routes to target compounds.
Ability to design innovative synthesis routes amenable to scale‑up for commercial production.
Develop route maps, conduct route scouting investigations to identify synthesis for process development.
Hands‑on experience in analytical and purification, including NMR, preparative chromatography, etc.
High level of creativity and productivity with strong synthetic chemistry problem solving skills.
The ability to effectively collaborate with international interdisciplinary teams of scientists and to capture and maintain appropriate records and effectively communicate results is essential.
Strong written and verbal communication skills are required.
ADDITIONAL NOTES/DESIRED SKILLS
Self‑motivated, with the ability to work proactively using own initiatives.
Hands‑on approach, with a 'can-do' attitude.