Patient-derived protein corona-engineered bionanoarchitectures for personalized PDAC therapy

Dipartimento di Medicina Molecolare- Sapienza università di Roma

Italia

In loco

EUR 30.000 - 55.000

Tempo pieno

8 giorni fa

Generatore di candidature

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Descrizione del lavoro

The Dipartimento di Medicina Molecolare- Sapienza università di Roma invites applications for a senior research position focused on oncological nanomedicine and cell/molecular biology. Candidates should have experience in developing and preclinical evaluation of nanostructured drug/gene delivery systems and in vitro/in vivo assessments relevant to cancer models.

Expertise in lipid nanoparticles or other nanocarriers and knowledge of nano-bio interactions, protein corona, and gene expression

Descrizione del lavoro

Organisation/Company Dipartimento di Medicina Molecolare- Sapienza università di Roma Research Field Medical sciences » Other Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 24 Sep 2026 - 23:59 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The candidate will need to have solid experience in oncological nanomedicine and cell and molecular biology, with particular reference to the development and preclinical evaluation of nanostructured systems for drug and gene delivery. Expertise is required in the preparation and physicochemical characterization of lipid nanoparticles and/or other nanocarriers, in the study of nano-bio interactions and protein corona, as well as in vitro evaluation by cell culture, viability/cytotoxicity assays, uptake and internalization, gene transfection and/or silencing, and expression analysis of molecular targets. Experience in in vivo preclinical studies, including evaluation of therapeutic efficacy, biodistribution and biological response in tumor animal models, is also required. Knowledge of animal testing procedures and possession of the relevant enabling training/certification shall be considered as highly preferential qualifications

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