Lead Scientist, Human Organoids for GBA1 Parkinson’s

European Academy of Bozen/Bolzano

Italy

On-site

EUR 50,000 - 52,000

Full time

2 days ago

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Benefits offered by this job

Welfare package supporting well-being

International collaboration with Chaŕ

Dynamic international research setting

Job summary

The Institute for Biomedicine at Eurac Research in Bolzano offers a three-year full-time postdoc position focused on leading the biology workstream of a Parkinson's disease NAM platform. You will drive development of hiPSC-derived brain organoids, apply cutting-edge readouts, and collaborate with partners in Bolzano and Berlin to translate disease signatures into testable therapies.

Ideal candidates hold a PhD in a biomedical field, have 3–6 years postdoc experience, and possess strong expertise

Qualifications

PhD in cell biology, developmental biology, neuroscience, bioengineering, toxicology, or related field.
3–6 years of postdoctoral experience after PhD.
Hands-on expertise in advanced human cell models (brain organoids, neural 3D cultures, hiPSC-derived models).
Experience with complex in vitro human model systems for neuro biology, translational disease modelling.

Responsibilities

Lead development, optimisation, and application of hiPSC-derived midbrain organoids and NAMs for GBA1-related Parkinson’s disease.
Design workflows to characterise disease mechanisms using molecular/phenotypic readouts (high-content imaging, electrophysiology).
Establish robust organoid workflows with standardisation and documentation.
Benchmark NAMs against human brain tissues for translational value.
Collaborate with proteomics, lipidomics, clinical partners for multi-omic integration.
Support quality frameworks and reproducibility in NAM workflows.
Provide scientific guidance and supervise junior researchers; contribute to publications and funding.