Postdoctoral Researcher - Circuit Reconstruction & Regenerative Neuroscience, Department of Neu[...]

Abcd IT; Piemonte; In loco; EUR 50.000 - 70.000; Tempo pieno

Descrizione del lavoro

A prestigious research institution in Italy is seeking a Postdoctoral Researcher to work on circuit reconstruction and regenerative neuroscience. This role involves devising strategies for single‑neuron mapping, analyzing various datasets, and developing bioinformatics pipelines. Candidates need a PhD in a relevant field and proficiency in R/Python. The offer includes a full-time position with an initial 2-year contract, competitive salary, and a stimulating multidisciplinary environment.

Competenze

• PhD in neuroscience, bioinformatics/computational biology, bioengineering or related.
• Track record in omics, molecular barcoding, and circuit tracing.
• Proficiency in R/Python; experience in high‑dimensional data statistics.

Mansioni

• Devise strategies for single‑neuron input/output mapping.
• Analyze transcriptomics datasets and integrate multi‑omics.
• Develop and maintain bioinformatics pipelines.

Conoscenze

Single‑cell/spatial omics

Molecular barcoding

Viral circuit tracing

Proficiency in R

Proficiency in Python

Statistical analysis for high‑dimensional data

Formazione

PhD in neuroscience or related field

Descrizione del lavoro

Postdoctoral Researcher – Circuit Reconstruction & Regenerative Neuroscience (ERC CUSTOM_MADE)

Department of Neuroscience, University of Turin, Italy

Project

We aim to rebuild functional striatal circuits by grafting human striatal progenitors with optimized properties in preclinical models of Huntington’s disease, combining circuit‑tracing with single‑cell and spatial omics.

Responsibilities

• Devise strategies and tools for single‑neuron input/output mapping integrated with molecular profiling (e.g., viral barcoding, retro/anterograde tracers).
• Analyze single‑cell/nucleus and spatial transcriptomics datasets; integrate multi‑omics.
• Develop and maintain reproducible bioinformatics pipelines and contribute to data/documentation best practices.

Required qualifications and desired skills

• PhD in neuroscience, bioinformatics/computational biology, bioengineering or related.
• Track record in one or more: single‑cell/spatial omics, molecular barcoding, viral circuit tracing.
• Proficiency in R/Python; statistics for high‑dimensional data.
• Molecular biology experience (cloning/molecular barcodes technologies) is welcome.
• Nice to have (not required): hPSC engineering/differentiation (e.g., CRISPR/AAV).

Environment & resources

The candidate will integrate in a lab with strong multidisciplinary interests, and within a stimulating partnership across molecular neuroscience, bioengineering, stem cell, systems biology, and regenerative medicine.

Terms

• Full‑time, initial 2‑year contract with possibility of renewal; salary commensurate with experience.
• Start date: first half of 2026.

Please send one PDF to [e-mail] containing:
1. your CV
2. 1-page cover letter describing fit and a recent project
3. contact info for at least 2 referees.
Subject: Postdoc CUSTOM_MADE – YourName

Review is rolling until filled; shortlisted candidates will be invited to interview.