.NET Full-Stack Developer

Persistent Systems; Pune District; Hybrid; INR 4,000,000 - 6,000,000; Full time

Job summary

Persistent Systems is seeking a strong .NET Full-Stack Engineer to design, build, and operate scalable cloud-native applications while contributing across architecture, development, testing, and mentoring.

You will design and build scalable microservices using .NET Core, C#, and cloud-native architecture principles. Experience with PostgreSQL and RESTful APIs is required, with hands-on cloud deployment on Azure, AWS, or GCP, and proficiency with Docker and Kubernetes.

Qualifications

• Strong expertise in .NET Core, C#, REST APIs, and cloud integrations.
• Frontend experience with Angular, React, or Blazor.
• Experience with PostgreSQL, SQL Server, and Cosmos DB.
• Familiarity with DDD and Clean Architecture; healthcare domain is a plus.
• Serverless exposure to Azure Functions or AWS Lambda.
• Hands-on with Docker, Kubernetes, and CI/CD tools.

Responsibilities

• Develop, optimize, and tune database components, including SQL scripts, stored procedures, functions, indexing strategies, and queries.
• Work extensively with PostgreSQL as a mandatory database, along with SQL Server or Cosmos DB based on project needs.
• Design and implement robust RESTful APIs, including JSON request and response mapping, validations, and API contracts.
• Apply cloud best practices for deployment, scaling, monitoring, logging, and configuration management across Azure, AWS, or GCP.
• Implement automated unit and integration tests to ensure reliability across microservices.
• Contribute to containerization using Docker and deployments on Kubernetes-based platforms.
• Troubleshoot complex distributed systems using logs, metrics, and tracing to improve performance and reliability.
• Participate in architecture discussions, perform code reviews, and mentor junior engineers.

Skills

NET Core

C#

REST APIs

Cloud integrations

Angular

React

Blazor

DDD

Clean Architecture

Healthcare domain

Azure Functions / AWS Lambda

Azure / AWS / GCP

PostgreSQL

SQL Server

Cosmos DB

Kafka

NUnit / xUnit

Moq

API testing tools

Docker

Kubernetes

CI/CD tools

Azure DevOps / Jenkins / GitLab CI

Infrastructure as Code

APIs design

Education

Master’s or PhD in Life Sciences, Biomedical Sciences, Clinical Research, Biotechnology, Translational Medicine, or related discipline

Tools

Docker

Kubernetes

Azure DevOps

Jenkins

GitLab CI

Infrastructure as Code

Job description

This role requires a strong .NET Full-Stack Engineer who can design, build, and operate scalable cloud-native applications while contributing across architecture, development, testing, and mentoring. Design and build highly scalable microservices using .NET Core, C#, and cloud-native architecture principles.

• Location: All Persistent Location
• Experience: 8 to 12 Years
• Job Type: Full-Time Employment

What You'll Do:

• Develop, optimize, and tune database components, including SQL scripts, stored procedures, functions, indexing strategies, and queries.
• Work extensively with PostgreSQL as a mandatory database, along with SQL Server or Cosmos DB based on project needs.
• Design and implement robust RESTful APIs, including JSON request and response mapping, validations, and API contracts.
• Apply cloud best practices for deployment, scaling, monitoring, logging, and configuration management across Azure, AWS, or GCP.
• Implement automated unit and integration tests to ensure reliability across microservices.
• Contribute to containerization using Docker and deployments on Kubernetes-based platforms.
• Troubleshoot complex distributed systems using logs, metrics, and tracing to improve performance and reliability.
• Participate in architecture discussions, perform code reviews, and mentor junior engineers.
• Required Skills and Experience
• Backend (Mandatory): Strong expertise in .NET Core, C#, REST APIs, and cloud integrations.
• Frontend: Experience with Angular, React, or Blazor.
• Architecture: Exposure to Domain-Driven Design (DDD) and Clean Architecture principles.
• Domain Experience: Experience working in healthcare is preferred.
• Serverless: Familiarity with Azure Functions or AWS Lambda.
• Cloud Platforms (Mandatory): Hands-on experience with Azure, AWS, or GCP for application deployment and operations.
• Databases: Strong experience with PostgreSQL, SQL Server, and NoSQL databases such as Cosmos DB.
• Event-Driven Systems: Experience with Kafka and event-driven architecture patterns.
• Testing: Hands-on experience with unit testing frameworks such as NUnit or xUnit, mocking frameworks like Moq, and API testing tools.
• Cloud-Native and DevOps: Experience with Docker, Kubernetes, CI/CD tools such as Azure DevOps, Jenkins, or GitLab CI, and infrastructure-as-code concepts.
• APIs: Proven experience designing, implementing, and consuming scalable RESTful APIs.
• Preferred Qualifications
• Knowledge of observability tools such as Application Insights, Prometheus, Grafana, or the ELK stack.
• Experience with security best practices, including OAuth2, OpenID Connect, and API security.
• Prior experience leading modules and driving technical decisions.
• Experience with chatbot technologies such as AWS Lex or Google Dialogflow.
• Experience with Pandas for data manipulation and analysis.
• Knowledge of large language models (LLMs) and frameworks such as LangChain.
• Experience building AI solutions using tools and frameworks such as AI agents, CrewAI, LangChain, LangGraph, Generative AI, and agentic AI.
• Hands-on experience using AI productivity tools such as Copilot and vibe coding workflows.
• Proven ability to adapt to rapidly changing environments and drive innovation aligned with business needs.
• Ability to work independently with strong troubleshooting and problem-solving skills.

Expertise You'll Bring:

• Master’s or PhD in Life Sciences, Biomedical Sciences, Clinical Research, Biotechnology, Translational Medicine, or a related discipline.
• 10+ years of experience in program or project management within healthcare, life sciences, BioPharma, or biomedical research environments.
• Strong understanding of biomedical data ecosystems, including EHRs, claims data, registries, clinical outcomes, and observational research data.
• Experience managing programs involving AI/ML, GenAI, Knowledge Graphs, NLP, or data-driven healthcare platforms.
• Familiarity with biomedical ontologies and standards such as SNOMED CT, ICD, MedDRA, LOINC, or semantic data modeling frameworks.
• Working knowledge of clinical research workflows, translational research, pharmacovigilance, patient journey analysis, or evidence generation processes.
• Proven ability to manage large cross-functional teams and coordinate delivery across technical and scientific stakeholders.
• Strong stakeholder management and client engagement capabilities, particularly with global BioPharma organizations.
• Excellent communication, problem-solving, decision-making, and program governance skills.
• Ability to operate effectively in fast-paced, ambiguous, and evolving project environments with high accountability and ownership.
• Competitive salary and benefits package
• Culture focused on talent development with quarterly growth opportunities and company-sponsored higher education and certifications
• Opportunity to work with cutting-edge technologies
• Employee engagement initiatives such as project parties, flexible work hours, and Long Service awards
• Insurance coverage: group term life, personal accident, and Mediclaim hospitalization for self, spouse, two children, and parents

Values-Driven, People-Centric & Inclusive Work Environment:

Persistent is dedicated to fostering diversity and inclusion in the workplace. We invite applications from all qualified individuals, including those with disabilities, and regardless of gender or gender preference. We welcome diverse candidates from all backgrounds.

• We support hybrid work and flexible hours to fit diverse lifestyles.
• Our office is accessibility-friendly, with ergonomic setups and assistive technologies to support employees with physical disabilities.
• If you are a person with disabilities and have specific requirements, please inform us during the application process or at any time during your employment

Let’s unleash your full potential at Persistent - persistent.com/careers

“Persistent is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind.”