Senior Scientist, Downstream Bioprocess & Tech Transfer

Bristol Myers Squibb

Cruiserath

On-site

EUR 90,000 - 120,000

Full time

4 days ago
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Job summary

Bristol Myers Squibb is seeking a Senior Scientist for the Cruiserath facility in Ireland to lead downstream unit operations supporting commercial biologics manufacturing. You will guide tech transfers, troubleshoot processes, and interpret lab-scale studies to drive investigations and continuous improvement.

The role requires strong protein purification expertise, GMP knowledge, and the ability to write technical reports and regulatory submissions.

Qualifications

  • Degree in chemical or biochemical engineering, biochemistry, biotechnology or a related scientific discipline.
  • Bachelor's degree with 7+ years, Master's with 5+ years, or PhD with 2–4 years relevant experience.
  • Strong understanding of protein purification, stability and downstream process performance.
  • Experience with downstream processing operations and equipment including chromatography and ultrafiltration/diafiltration.

Responsibilities

  • Provide technical leadership and SME for downstream unit operations supporting commercial biologics manufacturing.
  • Led tech transfer of commercial and pipeline assets to Cruiserath site and wider network with technical oversight and recommendations.
  • Lead or support process troubleshooting, root cause analysis, investigations, and CAPA development.
  • Design, execute and interpret lab-scale studies supporting investigations, process understanding and tech transfer.
  • Author/review study protocols, technical reports, regulatory submissions, and responses to technical enquiries.
  • Drive continuous improvement to enhance process robustness, efficiency, compliance and knowledge management.
  • Collaborate with MS&T, Manufacturing, Quality, Process Development, Analytical, Regulatory and external partners to align strategy and execution.
  • Evaluate emerging downstream technologies and recommend fit-for-purpose improvements.

Skills

Protein purification
GMP knowledge
Technical writing
Stakeholder communication
Process troubleshooting

Education

Bachelor's degree in chemical/biochemical engineering
Master's degree in related field
PhD in relevant discipline

Tools

Chromatography systems
Ultrafiltration
Diafiltration

Job description

Bristol Myers Squibb is seeking a Senior Scientist for the Cruiserath facility in Ireland to lead downstream unit operations supporting commercial biologics manufacturing. You will guide tech transfers, troubleshoot processes, and interpret lab-scale studies to drive investigations and continuous improvement.

The role requires strong protein purification expertise, GMP knowledge, and the ability to write technical reports and regulatory submissions.

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