Biologics Downstream Lab Lead – Process Science

Merck; Ireland; On-site; EUR 90,000 - 130,000; Full time

Job summary

Merck in Dunboyne, Co. Meath, Ireland, is seeking a Downstream Process Science Lab Technical Lead to drive technical leadership across the Process Sciences Lab.

The role supports biological manufacturing from development to commercial readiness, with emphasis on downstream purification, viral clearance, and process optimisation. The successful candidate will lead a cross-functional team, ensure GMP and data integrity, and contribute to continuous improvement and knowledge sharing across the MS&T

Qualifications

• Degree in a Science/Technical field; MSc/PhD desirable for advanced expertise.
• Minimum 6 years' experience in biopharmaceutical development, manufacturing support or MS&T.
• Strong understanding of GMP, data integrity and quality systems in lab and manufacturing settings.
• Proven ability to interpret complex data and translate findings into manufacturing actions.

Responsibilities

• Lead Downstream scientists in design and execution of scale-down studies and process improvements.
• Oversee small-scale studies to support technology transfer, facility fit and lifecycle changes.
• Provide technical leadership for downstream purification, filtration, viral clearance, UF/DF and formulation work.
• Support new product introductions across Drug Substance programs with cross-functional teams.
• Mentor and coach team members to drive continuous learning, problem solving and innovation.

Skills

Biologics

Biopharmaceuticals

Cell Cultures

Downstream Operations

GMP

Lab Processing

Manufacturing

Technology Transfer

Education

Science/Technical degree

MSc or PhD desirable

Job description

Merck in Dunboyne, Co. Meath, Ireland, is seeking a Downstream Process Science Lab Technical Lead to drive technical leadership across the Process Sciences Lab.

The role supports biological manufacturing from development to commercial readiness, with emphasis on downstream purification, viral clearance, and process optimisation. The successful candidate will lead a cross-functional team, ensure GMP and data integrity, and contribute to continuous improvement and knowledge sharing across the MS&T