Lead Upstream Process Science Lab – Biologics

Merck Gruppe - MSD Sharp & Dohme; Dunboyne; Remote; EUR 90,000 - 120,000; Full time

Job summary

Merck Gruppe - MSD Sharp & Dohme in Dunboyne, Co. Meath, Ireland is seeking an Upstream Process Science Lab Technical Lead to drive technical leadership in the Process Sciences Lab and enable biologics manufacturing at the site.

The role leads a team of Upstream scientists, designs and executes scale-down studies, supports technology transfer, and ensures GMP, data integrity, and quality systems are embedded across laboratory and manufacturing activities while collaborating across global MS&T

Qualifications

• A degree qualification in a relevant field (Science/Technical). An Advanced Degree (MSc or PhD) qualification is desirable.
• A minimum of 6 years’ experience working in biopharmaceutical development, manufacturing support, MS&T, process sciences, or technical operations, with extensive experience in Upstream biologics operations.
• Strong understanding of GMP, regulatory expectations, data integrity, and quality systems relevant to laboratory and manufacturing support activities.
• Proven ability to interpret complex datasets, solve technical problems, and convert scientific findings into practical manufacturing actions.
• Effective communicator with the ability to think logically and be proactive under pressure and work as part of a cross-functional team.

Responsibilities

• Management of a team of Upstream scientists involving the design, planning and execution of scale-down model establishment, satellite, and improvement studies in the Process Sciences Lab.
• Oversee the design and execution of small-scale studies which support Dunboyne site and network technology transfer, facility fit, process characterisation, and lifecycle change.
• Provide technical leadership for laboratory studies supporting upstream unit operations such as cell culture, harvest, and process scale-down model execution.
• Provision of technical expertise and leadership to support successful new product introduction across all Drug Substance and Cell Banking programs at the site.
• Lead and coach others to solve problems and take new perspectives on existing solutions with a desire to continuously learn, improve and develop.
• Excellent troubleshooting and problem-solving skills as well as influencing, collaboration skills and teamworking ability to represent MS&T on global and interdisciplinary teams.
• Champion a proactive safety, quality, and compliance culture within all laboratory activities within an open and inclusive team culture.

Skills

Problem solving

Cross-functional collaboration

Effective communication

GMP/regulatory understanding

Education

Degree in Science/Technical

Advanced Degree (MSc/PhD) desirable

Job description

Merck Gruppe - MSD Sharp & Dohme in Dunboyne, Co. Meath, Ireland is seeking an Upstream Process Science Lab Technical Lead to drive technical leadership in the Process Sciences Lab and enable biologics manufacturing at the site.

The role leads a team of Upstream scientists, designs and executes scale-down studies, supports technology transfer, and ensures GMP, data integrity, and quality systems are embedded across laboratory and manufacturing activities while collaborating across global MS&T