VP, In Silico Therapeutics & Design Leadership

Evotec; Abingdon; Hybrid; GBP 150,000 - 210,000; Full time

Job summary

Evotec is seeking a Vice President, Head of Therapeutics Design to lead the in silico design capability across small molecules, peptides, proteins and degraders, integrating computational chemistry with multi-omics data to drive decision making.

You will set the technical vision, build and lead a distributed team across Abingdon, UK and Verona, Italy, partner with Strategy & Portfolio, and position Evotec as a partner of choice in AI-powered drug discovery.

Qualifications

• PhD in computational chemistry, medicinal chemistry, cheminformatics, structural biology or related field.
• Significant biotech/pharma drug-discovery design experience.
• Proven track record progressing molecules to development candidates or clinical assets.
• Senior leadership with budget and multi-site team accountability.
• External scientific profile via publications, patents or conferences.
• Fluent business English

Responsibilities

• Set the technical vision for therapeutics design across modalities.
• Own ADMET/Safety as a strategic capability anchored in data.
• Guide design decisions using target biology and multi-omics data.
• Contribute to flagship programmes with shared roadmaps and delivery.
• Industrialise capabilities with repeatable, validated methods across partnerships.
• Build and develop a distributed scientific team across sites.
• Enable commercial value through partnerships and asset licensing.
• Act as external voice for Evotec therapeutics design with partners and conferences.

Skills

Computational chemistry

Medicinal chemistry

Generative design

ADMET modelling

Protein modelling

ML in drug discovery

RDKit

Python

Leadership

Executive communication

Education

PhD in computational/medicinal chemistry or cheminformatics

Tools

RDKit

Python

Cloud HPC

Job description

Evotec is seeking a Vice President, Head of Therapeutics Design to lead the in silico design capability across small molecules, peptides, proteins and degraders, integrating computational chemistry with multi-omics data to drive decision making.

You will set the technical vision, build and lead a distributed team across Abingdon, UK and Verona, Italy, partner with Strategy & Portfolio, and position Evotec as a partner of choice in AI-powered drug discovery.