Structural Biologist - Molecular Modelling & Biophysics

UCB

Slough

Hybrid

GBP 70,000 - 105,000

Full time

14 days+

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Job summary

UCB is seeking a collaborative Structural Biologist to join the Characterization and Material Sciences team in Slough, United Kingdom. You will apply computational and biophysical approaches to support the development of innovative therapies, using molecular modelling and predictive techniques to characterize molecules and accelerate development from research through to commercialization.

You will work with multidisciplinary teams across formulation, analytical sciences, and research functions,

Qualifications

  • Doctorate or Master’s degree with relevant experience in Structural Biology, Computational Biology, Biophysics, or a related scientific discipline.
  • Experience in protein homology modelling, molecular dynamics simulations, and computational structural biology.
  • Proficiency in Linux operating systems and scripting using Python or R.
  • Strong understanding of antibody structure, function, and biophysical characterization principles.
  • Ability to manage multiple priorities, work independently, and collaborate effectively with diverse stakeholders.
  • Excellent written and verbal communication skills, with experience preparing scientific reports and technical documentation.

Responsibilities

  • Apply molecular modelling and simulation techniques to characterize proteins, peptides, polymers, and small molecules.
  • Develop, maintain, and optimize scripts to automate structural modelling and molecular dynamics workflows.
  • Build predictive models that support and accelerate therapeutic development programmes.
  • Collaborate with cross-functional scientific teams to address complex development and characterization challenges.
  • Contribute to technical reports, procedures, protocols, and regulatory documentation.
  • Perform laboratory-based biophysical characterization activities when required.

Skills

Molecular modelling
Molecular dynamics
Python
R
Biophysics knowledge

Education

PhD in Structural Biology or related field
Master's in a relevant field

Tools

Linux
Python scripting
Molecular modelling software
Molecular dynamics packages (Gromacs, etc.)

Job description

UCB is seeking a collaborative Structural Biologist to join the Characterization and Material Sciences team in Slough, United Kingdom. You will apply computational and biophysical approaches to support the development of innovative therapies, using molecular modelling and predictive techniques to characterize molecules and accelerate development from research through to commercialization.

You will work with multidisciplinary teams across formulation, analytical sciences, and research functions,

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