Structural Biologist

UCB S.A.; Princes Risborough; Hybrid; GBP 60,000 - 90,000; Full time

Job summary

UCB is a global biopharmaceutical company. We are seeking a skilled Computational Biologist to apply molecular modelling and simulation techniques to characterize proteins, peptides, polymers, and small molecules. You will develop scripts to automate workflows and collaborate with cross-functional teams across the UK and beyond.

Hybrid work arrangement applies, with 40% time in the office. The role emphasizes data-driven biophysical characterization and regulatory-quality documentation in

Qualifications

• Doctorate or Master’s degree in a relevant field.
• Experience in Structural Biology, Computational Biology, Biophysics, or related discipline.
• Practical experience in protein homology modelling, molecular dynamics simulations, and computational structural biology.
• Proficiency in Linux and scripting with Python or R.
• Strong understanding of antibody structure, function, and biophysical characterization concepts.
• Ability to manage multiple priorities, work independently, and collaborate with diverse stakeholders.
• Excellent written and verbal communication skills, with experience preparing scientific reports and technical documentation.

Responsibilities

• Apply molecular modelling and simulation techniques to characterize proteins, peptides, polymers, and small molecules.
• Develop, maintain, and optimize scripts to automate structural modelling and molecular dynamics workflows.
• Build predictive models to support and accelerate therapeutic development programmes.
• Collaborate with cross-functional scientific teams to address complex development and characterization challenges.
• Contribute to technical reports, procedures, protocols, and regulatory documentation.
• Perform laboratory-based biophysical characterization activities when required.

Skills

Structural Biology

Computational Biology

Biophysics

Antibody structure

Multiple priorities

Scientific reporting

Education

Doctorate or Master’s degree

Tools

Linux

Python

R

Job description

computational techniques. You will collaborate closely with colleagues across formulation, analytical sciences, drug substance, drug product, and research functions, as well as academic and external partners across the United Kingdom, Belgium, Switzerland, and the United States.

What you'll do

Apply molecular modelling and simulation techniques to characterize proteins, peptides, polymers, and small molecules. Develop, maintain, and optimize scripts to automate structural modelling and molecular dynamics workflows. Build predictive models that support and accelerate therapeutic development programmes. Collaborate with cross-functional scientific teams to address complex development and characterization challenges. Contribute to technical reports, procedures, protocols, and regulatory documentation. Perform laboratory-based biophysical characterization activities when required.

About us

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe, inspired by patients and driven by science.

Why work with us?

At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. At UCB, we've embraced a hybrid-first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on #####.

Qualifications

we're looking for the, following education, experience and skillsDoctorate or Master's degree

• with relevant experience in Structural Biology, Computational Biology, Biophysics, or a related scientific discipline
• Practical experience in protein homology modelling, molecular dynamics simulations, and computational structural biology.
• Proficiency in Linux operating systems and scripting using Python or R programming languages.
• Strong understanding of antibody structure, function, and biophysical characterization principles.
• Ability to manage multiple priorities, work independently, and collaborate effectively with diverse stakeholders.
• Excellent written and verbal communication skills, with experience preparing scientific reports and technical documentation.

If this sounds like you, then we would love to hear from you!

Job Summary

Job number: 93632Date posted : 2026-07-22Profession: Engineering, Manufacturing & Supply ChainEmployment type: Permanent