Senior Scientist - Purification Development

TN United Kingdom; Slough; On-site; GBP 40,000 - 80,000; Full time

Job summary

An established industry player in life sciences is seeking a Senior Scientist to lead purification development for monoclonal antibodies. This role involves designing high throughput chromatography methods, managing projects, and ensuring compliance with GLP/GMP standards. The ideal candidate will have a strong background in protein chemistry, excellent laboratory skills, and the ability to work in a fast-paced environment. Join a team that values innovation and collaboration, where your contributions will make a significant impact in the field of biotechnology.

Qualifications

• BSc or PhD in Biotechnology or relevant scientific discipline with laboratory experience.
• Experience with Tecan Evo and/or Fluent programming.
• Knowledge of GLP/GMP standards.

Responsibilities

• Plan and design experiments for downstream process development of therapeutic proteins.
• Manage projects ensuring safety, quality, and accuracy.
• Collaborate within cross-functional project teams.

Skills

Protein Chemistry

Chromatography

Laboratory Skills

Data Analysis

Communication Skills

Problem-Solving

Project Management

Stakeholder Management

Attention to Detail

Time Management

Education

BSc in Biotechnology

PhD in Biotechnology

Tools

Tecan Evo

Unicorn Software

AKTA Chromatography

Job description

Senior Scientist - Purification Development, Slough

Lonza is a global leader in life sciences, operating across five continents. We value talented people working together to devise ideas that help businesses and improve lives. We support our employees' careers and foster an environment where their ideas can make a real impact.

Job Overview

Develop, evaluate, characterize, and validate protein purification processes for monoclonal antibodies and other recombinant proteins. Support transfer of these processes to pilot and GMP scale.

Key Responsibilities

1. Plan and design experiments for downstream process development of therapeutic proteins.
2. Design and execute high throughput chromatography methods.
3. Manage own projects, ensuring safety, quality, timeliness, and accuracy.
4. Escalate technical issues promptly.
5. Record experimental details, raw data, and results accurately.
6. Analyze data to produce high-quality process information.
7. Collaborate within cross-functional project teams.
8. Prepare and deliver presentations, protocols, and reports.
9. Maintain up-to-date training.
10. Contribute to laboratory efficiency.

Key Requirements

1. BSc or PhD in Biotechnology or relevant scientific discipline with laboratory experience.
2. Experience with Tecan Evo and/or Fluent programming.
3. Knowledge of protein chemistry and purification.
4. Strong practical laboratory skills.
5. Experience with laboratory scale AKTA chromatography.
6. Excellent communication skills.
7. Strong planning and organizational skills.
8. Proficiency in Unicorn software.
9. Knowledge of GLP/GMP standards.
10. Experience with process transfer and scale-up to cGMP manufacturing.
11. Stakeholder management experience.
12. Knowledge of GAP analysis methodologies.
13. Experience in process characterization and validation.
14. Operational excellence experience (e.g., 5S).

Qualities and Attitudes

1. Attention to detail.
2. Effective interpersonal skills.
3. Time management and prioritization.
4. Problem-solving initiative.
5. Ability to work independently and in fast-paced environments.
6. Willingness to support departmental activities.

At Lonza, we are committed to ethical success, respecting our people and environment. We offer challenging opportunities to solve complex problems and develop new ideas in life sciences, making a meaningful difference worldwide.