Scientist - Purification Development

Lonza Biologics Porriño SLU; Slough; On-site; GBP 30,000 - 60,000; Full time

Job summary

Join a forward-thinking company dedicated to life sciences, where your expertise in protein purification can make a real difference. In this exciting role, you will have the opportunity to develop and validate processes for monoclonal antibodies, working closely with a talented team. You'll be responsible for planning experiments, analyzing data, and ensuring the highest quality standards in a fast-paced environment. If you're passionate about science and eager to contribute to meaningful projects that improve lives, this is the perfect opportunity for you to thrive and grow your career.

Qualifications

• BSc/PhD in Biotechnology or relevant field with lab experience.
• Strong practical skills in protein purification and chromatography.

Responsibilities

• Plan and design experiments with guidance from lead scientist.
• Ensure quality and safety in project execution and delivery.

Skills

Protein Chemistry

Protein Purification

Laboratory Skills

Communication Skills

Planning and Organizational Skills

Problem Solving

Education

BSc in Biotechnology

PhD in a relevant scientific discipline

Tools

AKTA Chromatography

Ultrafiltration Systems

Unicorn Software

Job description

Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

To develop, evaluate, characterise and validate protein purification processes for monoclonal antibodies and other recombinant proteins and support the transfer of these processes to pilot and GMP scale.

Key responsibilities:

1. Plan and design own experiments with guidance from lead scientist
2. Responsible for the execution and delivery of own projects with particular attention to safety, quality, on time and right first time
3. Escalate technical issues in a timely fashion
4. Ensure that experimental details, raw data and results are recorded appropriately
5. Collate, analyse and evaluate data to produce good quality process information
6. Operate as part of a cross-functional project team
7. Prepare and deliver high quality presentations, protocols and reports
8. Ensure own training is up to date
9. Contribute to the efficient running of the laboratories

Key requirements:

1. BSc / PhD in Biotechnology or in a relevant scientific discipline and appropriate laboratory experience.
2. Theoretical knowledge of protein chemistry and protein purification
3. Strong practical laboratory skills
4. Practical experience with laboratory scale AKTA chromatography and ultrafiltration (TFF) systems
5. Strong written and verbal communication skills
6. Strong planning and organisational skills
7. Proficient in the use of Unicorn software
8. Knowledge of GLP / GMP
9. Experience of process transfer and scale up to cGMP manufacture
10. Knowledge of GAP analysis methodologies (e.g. FMEA, Cause and effect analysis)
11. Experience of process characterisation / validation
12. Operational excellence (5S or similar) experience

Qualities and Attitude:

1. Excellent attention to detail
2. Must have excellent interpersonal skills to work effectively as part of a multidisciplinary/project team
3. Prioritise and manage own time effectively
4. Show initiative for problem solving and generating new ideas
5. Work independently to an agreed plan
6. Able to work with minimal supervision
7. Comfortable working in a fast paced environment with changing priorities
8. Willingness to support other activities within the department

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.