Senior Scientist - High-Content Plant Cell Imaging & Screening

Ellison Institute, LLC; Oxford; Hybrid; GBP 70,000 - 100,000; Full time

Benefits offered by this job

Enhanced holiday

Pension - Employer contribution 7.5%

Private Medical Insurance

Cycle to Work Scheme

Family Planning

Job summary

The Ellison Institute of Technology in Oxford is seeking a Scientist in High-Throughput High-Content Imaging and Cell Phenotypic Screening to build an automated imaging platform for plant cells.

You will work with automation and AI teams to develop scalable screening workflows and contribute to publications and IP generation, translating research into real-world applications aligned with EIT’s mission.

Qualifications

• PhD in cell biology or related discipline with relevant postdoctoral experience in industry or academia.
• Demonstrated experience in developing and optimising quantitative, image-based cellular assay, including high-throughput or high-content screening workflows.
• Extensive hands-on experience with imaging of cells or tissues using widefield, fluorescence, confocal microscopy or other advanced microscopy platforms.
• Strong understanding of cellular phenotypes and ability to translate biological questions into measurable imaging readouts.
• Experience with quantitative image analysis, including segmentation, feature extraction, and phenotypic classification.

Responsibilities

• Design and optimise high-throughput, image-based phenotypic screening workflow for plant cell systems.
• Develop robust cell-based imaging assays to quantify phenotypes including cell growth, division, morphology, viability and cell-state changes.
• Design and optimise fluorescence-based assays and reporter system for quantitative phenotypic screening.
• Establish reproducible image acquisition and analysis pipeline, including segmentation, feature extraction and phenotypic classification.
• Evaluate and implement appropriate microscopy technologies, including high-content imaging, confocal and other approaches according to experimental needs.
• Design rigorous screening experiments with appropriate controls, replications and statistical analysis.
• Analyse, interpret and communicate results. Using findings to guide biological validation and subsequent design-build-test-learn cycles.
• Work closely with automation teams to integrate imaging workflows for scalable screening.
• Collaborate with bioinformatic and AI team to develop and validate advanced image-analysis and phenotype classification.

Skills

High-content imaging

Microscopy expertise

Image analysis

Collaboration with AI/data teams

Experimental workflow design

Education

PhD in cell biology or related

Tools

Widefield fluorescence microscopy

Confocal microscopy

Image analysis software

Automation integration experience

Job description

The Ellison Institute of Technology in Oxford is seeking a Scientist in High-Throughput High-Content Imaging and Cell Phenotypic Screening to build an automated imaging platform for plant cells.

You will work with automation and AI teams to develop scalable screening workflows and contribute to publications and IP generation, translating research into real-world applications aligned with EIT’s mission.