Senior Manager, Global Patient Safety — Lead Signals

Regeneron Pharmaceuticals; Uxbridge; Hybrid; GBP 90,000 - 130,000; Full time

Job summary

Regeneron Pharmaceuticals in the United Kingdom seeks a Senior Manager for Global Patient Safety (GPS) to lead safety strategies for molecules in development and post‑marketing. You will aggregate, review and analyze safety data to support risk assessment, contribute to DSUR/PSUR/RMP, and present findings to SMT and cross‑functional teams.

The role requires advanced degrees and 7+ years in pharmacovigilance or risk management, with strong regulatory knowledge and proactive, clear communication.

Qualifications

• Master’s, PhD, or PharmD required.
• 7+ years of risk management experience in pharma/biotech or health authority.
• Ability to apply FDA, EU and ICH pharmacovigilance guidelines.
• Experience with safety system databases for medical case reviews.
• Proactive, self-disciplined, able to meet deadlines and prioritize.
• Excellent verbal and written safety communication skills.

Responsibilities

• Complete signal detection activities per safety surveillance plan.
• Evaluate signals and author safety evaluations.
• Prepare and review DSUR, PSUR, and RMP documents.
• Prepare and deliver SMT presentations; participate in study teams.
• Engage in risk management activities for assigned compounds.
• Represent GPS on cross‑functional teams (RSOC, IDMC, etc.).
• Contribute to SOPs, WIs and supporting documents.

Skills

Signal detection

Signal evaluation

Safety documentation

Safety reporting

Cross-functional collaboration

Communication

Education

Master’s degree

PhD

PharmD

Tools

Safety database

Job description

Regeneron Pharmaceuticals in the United Kingdom seeks a Senior Manager for Global Patient Safety (GPS) to lead safety strategies for molecules in development and post‑marketing. You will aggregate, review and analyze safety data to support risk assessment, contribute to DSUR/PSUR/RMP, and present findings to SMT and cross‑functional teams.

The role requires advanced degrees and 7+ years in pharmacovigilance or risk management, with strong regulatory knowledge and proactive, clear communication.