Senior Mammalian Expression Scientist – CHO & GMP

Lonza, Inc.

Saffron Walden

On-site

Confidential

Full time

2 days ago
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Job summary

Lonza in Cambridge, UK is seeking a senior scientist to lead mammalian expression projects. You will perform hands-on lab work and drive project delivery, with emphasis on CHO-based expression systems and newer host development.

The role requires a PhD with strong experience in CHO engineering, molecular biology, and data interpretation. You will mentor colleagues and collaborate across disciplines to enable GMP-ready technology transfer.

Qualifications

  • Strong practical expertise in CHO cell line engineering and mammalian expression system development
  • Hands-on experience in molecular biology and expression systems development
  • Experience leading scientific projects and mentoring colleagues
  • Collaborative, proactive communicator with cross-disciplinary teamwork
  • Experience in experimental design and statistics to turn data into conclusions

Responsibilities

  • Lead key mammalian cell expression projects with ~80% hands-on lab work
  • Develop and contribute to next-generation CHO-based expression hosts
  • Engineer mammalian cell lines using random and targeted integration and CRISPR
  • Develop expression vectors using state-of-the-art molecular biology techniques
  • Characterise engineered cell lines using NGS, ddPCR, qPCR, flow cytometry
  • Analyse data, sign off results, and communicate findings in reports
  • Mentor junior scientists and support knowledge sharing and project delivery
  • Drive technology development and transfer towards GMP manufacturing
  • Build expertise through internal stakeholder engagement and proof-of-concept projects

Education

PhD or equivalent advanced scientific qualification

Job description

Lonza in Cambridge, UK is seeking a senior scientist to lead mammalian expression projects. You will perform hands-on lab work and drive project delivery, with emphasis on CHO-based expression systems and newer host development.

The role requires a PhD with strong experience in CHO engineering, molecular biology, and data interpretation. You will mentor colleagues and collaborate across disciplines to enable GMP-ready technology transfer.

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