Senior Bioinformatician - Oxford

Immunocore; Oxford; On-site; GBP 45,000 - 80,000; Full time

Job summary

An innovative biotechnology company is seeking a Senior Bioinformatician to join their dynamic team in Oxford. This role offers the opportunity to leverage cutting-edge bioinformatics expertise to analyze translational biomarker data, contributing to the development of groundbreaking therapies. You will work with a talented group of professionals, utilizing your skills in R, Python, and NGS pipelines to generate insights that drive scientific advancements. The company fosters a collaborative environment that values diversity and encourages personal growth, making it an exciting place to advance your career in the life sciences sector.

Qualifications

• Proficiency in bioinformatics tools and programming languages.
• Experience in data analysis and visualization.

Responsibilities

• Conduct analysis of transcriptomic and genomic sequencing data.
• Develop custom tools for data interpretation and visualization.
• Lead data analysis efforts and mentor colleagues.

Skills

R/Bioconductor

Linux OS

Shell scripting (bash)

Python programming

Molecular biology

Immunology

NGS analytical pipelines

Education

PhD in a relevant scientific discipline

MSc or BSc with equivalent research or industrial experience

Tools

SQL

Job description

Senior Bioinformatician - Oxford

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company dedicated to developing and commercializing innovative medicines for unmet patient needs in oncology, infectious diseases, and autoimmune diseases. Our R&D leaders are recognized globally as some of the industry's most successful drug developers. We foster an environment that encourages interaction among great minds and drives innovation to answer significant scientific questions.

We focus on delivering first-in-class biological therapies, utilizing a highly innovative soluble TCR platform. Our ImmTAX molecules represent a new generation of precision-engineered drugs that harness the immune system to treat diseases with high unmet medical needs, including oncology, infectious diseases, and autoimmune disorders. At Immunocore, our employees are our greatest asset.

We value each individual's unique contributions and uphold our core values: Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE). These principles create a collaborative environment where ideas flourish and transformative changes occur.

Our commitment is to develop breakthrough therapies that improve patients' lives, advance medicine, and support our team. Immunocore is an equal opportunity employer, committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered.

We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability, or other protected characteristics.

The role involves providing specialized bioinformatics expertise to support the analysis and data management of translational biomarker data. The candidate will explore publicly available data and emerging clinical trial data to generate insights into mechanisms of action, molecular heterogeneity, and novel targets.

Key Responsibilities

1. Conduct analysis of transcriptomic and genomic sequencing data from clinical trials.
2. Complement and develop scientific hypotheses through public data mining and analysis of in-house experiments.
3. Develop custom tools and analytics for data interpretation and visualization.
4. Contribute to scientific publications and presentations.
5. Maintain and enhance technical knowledge through self-study, conferences, and training.
6. Ensure accurate record-keeping and compliance with company procedures.
7. Operate in accordance with health and safety policies.

Specific Responsibilities

• Lead data analysis efforts, propose new analyses based on emerging data.
• Support technical aspects for team members.
• Establish work priorities aligned with team and project goals.
• Share knowledge across departments and mentor colleagues.
• Maintain detailed records of all work.
• Provide technical guidance on equipment use and new techniques.
• Promote health and safety practices and communicate research findings effectively.

Person Specification

Essential Experience and Knowledge

• Proficiency in R/Bioconductor, Linux OS, shell scripting (bash), and programming (preferably Python).
• Understanding of molecular biology, immunology, or related fields.
• Significant independent research experience in academia or industry.
• Experience with NGS analytical pipelines.

Desirable Skills

• Leadership experience in managing small projects or teams.
• Experience with database development (SQL) and data interfaces.
• Mentoring experience.
• Knowledge of machine learning or applied statistics.

Education & Qualifications

• PhD in a relevant scientific discipline with 2-5 years of experience (postdoctoral preferred).
• MSc or BSc with equivalent research or industrial experience.