Research Associate, Functional Genomics & Kidney Organoids

SONICOM; Greater London; On-site; GBP 38,000 - 48,000; Full time

Benefits offered by this job

Wet and dry lab training

Independent research ideas supported

Collaborative, diverse team culture

Job summary

Imperial College London invites applications for a postdoctoral Research Associate in Functional Genomics to join the Renal Genomics group. The role focuses on iPSC-derived kidney organoids, CRISPR perturbations, and multiomics profiling to understand kidney development and CAKUT.

You will collaborate with bioinformaticians and clinicians, publish advances in high-quality journals, and have opportunities to pursue independent ideas within the lab's core aims at Imperial's Hammersmith campus.

Qualifications

• PhD (or equivalent) in biology (stem cell/development/genomics/molecular biology).
• Experience with mammalian cell culture and molecular biology techniques.
• Interest in kidney development and disease biology.

Responsibilities

• Establish and run iPSC-derived kidney and ureteric bud organoid models.
• Use CRISPR interference to perturb candidate regulatory elements.
• Profile consequences with single-nucleus multiomics, CUT&RUN and low-input chromosome conformation capture.
• Collaborate with bioinformaticians and clinicians to test mechanistic hypotheses.
• Publish in peer-reviewed journals and present at conferences.
• Develop independent research ideas within the lab's focus.

Skills

Mammalian cell culture

Molecular biology skills

Stem cell biology

Developmental biology

Genomics / genetics

Education

PhD or equivalent in biology

Job description

Imperial College London invites applications for a postdoctoral Research Associate in Functional Genomics to join the Renal Genomics group. The role focuses on iPSC-derived kidney organoids, CRISPR perturbations, and multiomics profiling to understand kidney development and CAKUT.

You will collaborate with bioinformaticians and clinicians, publish advances in high-quality journals, and have opportunities to pursue independent ideas within the lab's core aims at Imperial's Hammersmith campus.