Cancer Imaging & Epigenomics Research Associate

University of Cambridge; Cambridge; On-site; GBP 39,000 - 52,000; Full time

Job summary

The University of Cambridge, CRUK Cambridge Institute, and the Wang Group are seeking an experienced Research Associate to develop and apply imaging and epigenomic methods. The position focuses on understanding gene regulation and oncogene amplification in cancer models, with potential work on ecDNA and intratumour heterogeneity.

The role offers opportunities to design experiments, build analyses pipelines, and contribute to publications, while mentoring junior researchers in a fast-paced,

Responsibilities

• Develop, validate and benchmark new imaging or sequencing methods, including probe or assay design, optimisation against reference standards, and documentation sufficient for others to use them.
• Apply advanced microscopy and/or epigenomic sequencing to questions of oncogene amplification, extrachromosomal DNA and gene-regulatory organisation in cancer models.
• Build and maintain analysis pipelines for large imaging or sequencing datasets, using institutional high-performance computing or cloud resources.
• Work with the Group Leader to formulate hypotheses and design experiments, and take the lead on interpretation and write-up of your own projects.
• Present findings at group meetings, Institute seminars and international conferences, and draft manuscripts for publication.
• Contribute to the day-to-day running of the laboratory, including equipment upkeep, protocol documentation and supply ordering.
• Train and mentor research assistants and students in the techniques and analyses within your area of expertise.

Job description

The University of Cambridge, CRUK Cambridge Institute, and the Wang Group are seeking an experienced Research Associate to develop and apply imaging and epigenomic methods. The position focuses on understanding gene regulation and oncogene amplification in cancer models, with potential work on ecDNA and intratumour heterogeneity.

The role offers opportunities to design experiments, build analyses pipelines, and contribute to publications, while mentoring junior researchers in a fast-paced,