Production Lead, GMP & Process Excellence

Piramal Pharma Limited; United Kingdom; On-site; GBP 22,000 - 32,000; Full time

Job summary

Piramal Pharma Limited in the United Kingdom is seeking an Executive-Production to oversee compression operations, supervise line staff, and ensure adherence to c-GMP and quality systems. You will coordinate manpower, optimize machine performance, and maintain accurate documentation across batches.

The role requires hands-on supervision of production lines, calibration checks, and active participation in validation activities.

Responsibilities

• Allocates workmen for different workstations on a shift-to-shift basis.
• Supervise line operations like weight verification, machine setting, initial parameter setting, and in-process checks.
• Review the batch manufacturing record and other quality documents.
• Fills in process parameters, Batch manufacturing record (BMR) and GMP documents/record as required by following ALCOA+ principles.
• Ensure no stoppage of operation/machines due to non-availability of manpower and any machine breakdown.
• Participates in Validation activities like Equipment/Area and Trial/Study/Pre-exhibit/Exhibit /validation batch activities as per the protocol.
• Maintains c-GMP practices along with documentation in various records.
• Handles minor parametric setting issues in various machines and products.
• Monitors the speed of the machine and output according to the run time.
• Reports on day-to-day basis activities in SAP system. (If SAP user ID is available)
• Verify/calibrate balances/Timer/Load cell/Encoder/Filling depth/timer Synchronization/etc on a daily/monthly basis.
• Participate in machine qualification activities as per Qualification protocol whenever required.
• Check all calibration/qualification tags of equipment, instruments, or fire extinguishers for their due date from time to time.
• Check line clearance during product changeover and batch changeover; monitor Temperature and RH/Pressure Gradient and area cleaning/disinfections.
• Knowledge and involvement in EHS, SFTI, 6S, ISO 14001 & 13485 activities.
• Fill safety checklist and provide toolbox talk training, report Unsafe condition/Unsafe act and Learning incident (Near miss).
• Perform and ensure that activities are carried out as per hazard identification and risk assessment (HIRA) and site EHS procedure (SEP).
• Provide training to the subordinates as and when required.
• Any other activity from time to time that his supervisor/company feels appropriate.

Skills

Line supervision

GMP compliance

Equipment setup

Batch record review

SAP reporting

Tools

SAP

Job description

Piramal Pharma Limited in the United Kingdom is seeking an Executive-Production to oversee compression operations, supervise line staff, and ensure adherence to c-GMP and quality systems. You will coordinate manpower, optimize machine performance, and maintain accurate documentation across batches.

The role requires hands-on supervision of production lines, calibration checks, and active participation in validation activities.