Principal Software Engineer - AI for Drug Discovery & Data

Roche Holding AG

Welwyn Hatfield

On-site

GBP 90,000 - 130,000

Full time

2 days ago

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Job summary

Roche Holding AG in the UK is seeking a Software Engineer (Principal / Senior Principal) to design and evolve modern computational and data ecosystems that accelerate drug discovery. You will build scalable, cloud-native platforms and interactive tooling that seamlessly integrate data, AI models, and workflows for scientists.

As a technical leader, you will mentor engineers, own architectural decisions, and partner with researchers to translate complex challenges into high-performance software

Qualifications

Ph.D. in life sciences or equivalent.
Experience building full-stack software in drug discovery environments.
Proficient in Python/Java and modern frontend frameworks.
Cloud deployments on AWS.

Responsibilities

Design and evolve modern computational and data ecosystems that accelerate drug discovery.
Build scalable, cloud-native platforms and interactive tooling for scientists.
Lead architectural decisions and promote SDLC best practices.
Mentor junior engineers and foster engineering excellence.
Collaborate with researchers to translate complex challenges into software solutions.
Drive AI-assisted development and agentic coding practices.

Skills

Full-stack engineering

Cloud architecture

AI-assisted development

Stakeholder collaboration

Mentorship

Education

Ph.D. or equivalent in life sciences

Tools

Python

Java

React

Vue

AWS

REST/GraphQL APIs

Job description

As a technical leader, you will mentor engineers, own architectural decisions, and partner with researchers to translate complex challenges into high-performance software

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