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Principal Scientist – Discovery & Translational Biology

Hyper Recruitment Solutions

Cambridgeshire and Peterborough

On-site

GBP 60,000 - 100,000

Full time

Today

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Job summary

An innovative drug-development start-up is seeking a Principal Scientist to lead efforts in oncology therapeutics. This role offers the chance to influence early drug development strategies while working with cutting-edge algorithms to discover novel protein fingerprints. The ideal candidate will have a strong background in developing Antibody Drug Conjugates and Bispecific Antibodies, as well as experience in a dynamic start-up environment. Join a team that is dedicated to improving patient outcomes through groundbreaking research in oncology. This is a unique opportunity to make a significant impact in the field.

Qualifications

PhD with significant experience in oncology biologics development.
Strong technical expertise in primary cell tissue culture and assay development.

Responsibilities

Develop novel oncology therapeutics and manage project delivery.
Support portfolio expansion through target validation and in vivo studies.

Skills

Oncology Therapeutics Development

Antibody Drug Conjugates (ADC)

Bispecific Antibodies

Primary Cell Tissue Culture

Flow Cytometry

IHC Assay Development

Education

PhD in Relevant Field

Principal Scientist – Discovery & Translational Biology

Join to apply for the Principal Scientist – Discovery & Translational Biology role at Hyper Recruitment Solutions

Principal Scientist – Discovery & Translational Biology

Join to apply for the Principal Scientist – Discovery & Translational Biology role at Hyper Recruitment Solutions

A fantastic opportunity has arisen for a Principal Scientist – Discovery & Translational Biology to join a high-potential drug-development start-up, who are focussed on developing new oncology therapeutics that significantly improve overall survival for patients with a high unmet need. Our client is at the cutting edge of oncology therapeutics, triggering a new wave in target discovery by using proprietary algorithms to identify novel protein fingerprints from a comprehensive membrane protein database.

They are in the process of establishing their own laboratory to execute their ambitious growth plans and seeking a highly motivated Principal Scientist to join their Research Group. This is an exciting opportunity for the right candidate to make a meaningful contribution across discovery and translational sciences.

Key Duties And Responsibilities

Your duties as the Principal Scientist will be varied however the key duties and responsibilities are as follows:

The ideal candidate will have hands-on experience in developing novel oncology therapeutics, ideally Antibody Drug Conjugates (ADC's) or Bispecific Antibodies. You will be adept at balancing delivery at the bench with project leadership, and have a proven track record of building successful relationships with external partners.
Joining a small team during a period of growth, this is a dynamic role that will allow the successful candidate to influence strategy on all aspects of early drug development.
You will support the portfolio expansion through target validation and co-expression studies, develop workflows for hit selection and lead triage, and delivering pivotal in vivo proof of concept data via external partners.

Role Requirements

To be successful in your application to this exciting role as the Principal Scientist we are looking to identify the following on your profile and past history:

Applicants will have a PhD in a relevant field, with significant experience in the development of novel oncology biologics, ideally Antibody Drug Conjugates (ADC's) or Bispecific Antibodies, gained predominantly within a commercial biotech or biopharma environment
Strong technical expertise in primary cell tissue culture, flow cytometry and IHC assay development and execution. Experience working with spheroids is desirable.
You must be comfortable working independently and pro-actively in a start-up environment.

Seniority level

Seniority level
Mid-Senior level

Employment type

Employment type
Full-time

Job function

Job function
Research, Analyst, and Information Technology
Industries
Staffing and Recruiting

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