Postdoctoral Research Scientist in Cardiovascular Sciences

TN United Kingdom; Oxford; Hybrid; GBP 30,000 - 40,000; Full time

Job summary

A leading research institution in Oxford is seeking a Postdoctoral Research Scientist in Cardiovascular Sciences. The role involves working on a BBSRC-funded project, focusing on human heart development mechanisms. Candidates should have a relevant PhD and experience in molecular biology. Responsibilities include managing research activities and collaborating with top researchers. The position offers hybrid working arrangements and comprehensive benefits.

Benefits

Hybrid working arrangements

Contributory pension scheme

38 days annual leave

Childcare services

Family leave schemes

Cycle and electric car loan schemes

Employee Assistance Programme

Membership to social and sports clubs

Discounted travel options

Qualifications

• Near completion of a PhD/DPhil in a relevant research area.
• Laboratory experience in molecular/cellular biology and/or genomics.

Responsibilities

• Manage research and administrative activities, coordinate projects.
• Collaborate with colleagues across Oxford, Cambridge, and partner institutions.
• Develop scientific techniques and protocols.

Skills

Organizational Skills

Communication

Interpersonal Skills

Education

PhD in relevant research area

Tools

Confocal Microscopy

Lightsheet Microscopy

Job description

Social network you want to login/join with:

Postdoctoral Research Scientist in Cardiovascular Sciences, Oxford

Client:

University of Oxford

Location:

Oxford, United Kingdom

Job Category:

Other

-

EU work permit required:

Yes

Job Reference:

fdbb2d4215f6

Job Views:

3

Posted:

17.05.2025

Expiry Date:

01.07.2025

Job Description:

We are seeking

a Postdoctoral Research Scientist to join our work with Dr Filipa Simões on a BBSRC-funded collaborative project as part of the consortium (CellTalkHDD) involving investigators from the University of Cambridge (Professor Sanjay Sinha - consortium lead PI; Dr Richard Tyser; Professor Sarah Teichman) and University of Oxford (Professor Paul Riley), studying the cellular and molecular mechanisms of human heart development.

The ideal candidate will hold, or be near completion of, a relevant PhD degree and have experience in molecular/cellular biology related to the work. They should be highly motivated with enthusiasm for science and possess good organizational, verbal, communication, and interpersonal skills. Ability to work independently and within a research team is essential. Experience in cardiovascular research, working with zebrafish models, and familiarity with hPSC-derived in vitro models, 2D/3D imaging, confocal, and lightsheet microscopy, would be advantageous.

This full-time position involves experimental work at the IDRM, with potential for some remote analytical work.

Key responsibilities:

• Manage own research and administrative activities, coordinate projects, meet deadlines, and support collaboration within the consortium.
• Collaborate with colleagues across Oxford, Cambridge, and partner institutions.
• Develop and adapt scientific techniques and protocols, including cell/molecular biology, genomics, tissue histology, embryology, and fluorescence imaging.
• Utilize human developmental heart cell atlas data to engineer in vitro 3D cardiac organoid models using human ES and iPS cells.
• Perform multimodal single-cell and spatial transcriptomics on zebrafish embryos and cardiac organoids, with subsequent validation and CRISPR-Cas9 gene editing.

Selection criteria:

• Near completion of a PhD/DPhil or equivalent in a relevant research area.
• Laboratory experience in molecular/cellular biology and/or genomics relevant to the project.
• Ability to contribute significantly to the research and lead in certain areas.
• Capability to obtain a Home Office personal license; training provided if needed.

What we offer:

• Hybrid working arrangements.
• Contributory pension scheme.
• 38 days annual leave.
• Childcare services.
• Family leave schemes.
• Cycle and electric car loan schemes.
• Employee Assistance Programme.
• Membership to social and sports clubs.
• Discounted travel options.