Post-doctoral Research Assistant

St George's, University of London; London; On-site; GBP 35,000 - 55,000; Full time

Job summary

An established industry player is seeking a dedicated Post-doctoral Research Assistant to lead groundbreaking research on Kv7.1 channels. This role requires a strong background in electrophysiology and cell culture techniques, as well as a PhD in a relevant field. You will be responsible for generating and analyzing data, presenting at conferences, and contributing to academic publications. Join a dynamic team committed to advancing knowledge in cardiac rhythmicity and make a significant impact in the field of medical sciences. If you are passionate about research and eager to explore new areas of study, this opportunity is perfect for you.

Qualifications

• Experience recording ion channel currents from mammalian systems.
• Desirable experience with immunocytochemistry and co-immunoprecipitation.

Responsibilities

• Generate and analyze data for the research project.
• Present findings at conferences and contribute to papers.

Skills

Electrophysiology

Cell Culture Techniques

Molecular Manipulation

Protein Biochemistry Techniques

Education

BSc in a relevant field

PhD in a relevant field

Job description

Join to apply for the Post-doctoral Research Assistant role at St George's, University of London.

Applications are sought for an experienced electrophysiologist to drive a project funded by the British Heart Foundation studying the regulation of Kv7.1 channels by βγ G proteins. This work builds upon a phenomenon identified by the research group, focusing on an ion channel important in cardiac rhythmicity. The successful candidate will be expected to generate and analyze data, present at conferences, contribute to writing papers and grant applications. As this is a new area of research, a positive and flexible mindset is required.

References

1. Stott JB, Povstyan OV, Carr G, Barrese V, Greenwood IA. G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity. Proc Natl Acad Sci U S A. 2015 May 19;112(20):6497-502. doi: 10.1073/pnas.1418605112. PMID: 25941381; PMCID: PMC4443360.
2. Stott JB, Greenwood IA. G protein βγ regulation of KCNQ-encoded voltage-dependent K channels. Front Physiol. 2024 Apr 9;15:1382904. doi: 10.3389/fphys.2024.1382904. PMID: 38655029; PMCID: PMC11035767.

Key Attributes of the Successful Applicant

• BSc and PhD in an appropriate field
• Experience recording ion channel currents from mammalian heterologous expression systems, especially whole cell and inside-out excised patch recordings
• Experience with cell culture techniques, including freezing and reanimation of cell lines
• Experience with molecular manipulation of plasmids to introduce amino acid changes or protein truncations
• Desirable: experience with protein biochemistry techniques such as immunocytochemistry, co-immunoprecipitation, and proximity ligation assay

For further information, contact Prof Iain Greenwood at [e-mail]. To apply, visit http://jobs.sgul.ac.uk.

St George’s School of Health and Medical Sciences is committed to promoting equality, diversity, and inclusion in all its activities, processes, and culture. Applications are welcome regardless of age, caring responsibilities, disability, gender identity, gender reassignment, marital status, nationality, pregnancy, race, ethnic origin, religion and belief, sex, sexual orientation, and socio-economic background.

Please quote reference: 113-25-R

Closing date: Tuesday 13 May 2025

Interview date: TBC

Seniority level

• Internship

Employment type

• Full-time

Job function

• Research, Analyst, and Information Technology

Industries

• Higher Education