Lead Phase I Clinical Research Physician

FTLEE Fortrea Clinical Research Unit Ltd; Leeds; On-site; GBP 110,000 - 150,000; Full time

Job summary

FTLEE Fortrea Clinical Research Unit Ltd in Leeds seeks an experienced Senior Clinical Research Physician to lead Phase I studies as Principal Investigator or Project Physician.

You'll work with our MHRA-accredited 100-bed unit, collaborating with nurses, pharmacy and wider clinical teams across early-phase studies, including healthy-volunteer populations, and contribute to safety oversight, data integrity and trial reporting.

Qualifications

• Established experience as a Principal Investigator in Phase I clinical trials, gained within an early-phase unit.
• Full GMC registration and current licence to practise medicine in the UK.

Responsibilities

• Take responsibility for assigned studies from start-up through closeout and the Clinical Study Report, working as Principal Investigator or Project Physician.
• Lead studies from the outset: join sponsor start-up meetings, review protocols and Investigator Brochures, assess feasibility, and support ethics and MHRA submissions.
• Collaborate with the wider Fortrea team including Med Sci, Project Management, Regulatory, Clinical Operations, Clinical Research Nurses and Pharmacy.
• Assess participant eligibility: screen participants and provide medical oversight throughout their involvement in the study.
• Lead clinical delivery: ensure studies are conducted according to protocol, ICH-GCP, internal SOPs across all clinical activities.
• Work closely with nursing and pharmacy to support the five Rs of dosing and the correct delivery of the investigational product.
• Safeguard participants: review adverse events, assess severity and causality, prepare serious adverse-event reports when required, and contribute to safety decisions.
• Partner with sponsors and CRAs: provide study updates, support decision-making, and work together to identify and resolve issues during study conduct.
• Maintain study quality: keep source documentation accurate, resolve data queries, and address issues as studies progress.
• Drive studies through closeout: work with the CRA and study team to ensure outstanding issues and data queries are resolved.
• Take accountability for the final report: contribute to the Clinical Study Report and confirm that the study was conducted according to protocol and accurately reported.
• Mentor less experienced colleagues: share your expertise with the Physician Associate and less experienced physicians.
• Represents the organization at scientific conferences, advisory boards and industry consortia

Skills

Clinical trial leadership

Phase I experience

Education

GMC registration and UK licence to practise

Diploma in Human Pharmacology or Pharmaceutical Medicine

Certificate of Completion of Training (CCT) in Clinical Pharmacology or Pharmaceutical Medicine

Job description

FTLEE Fortrea Clinical Research Unit Ltd in Leeds seeks an experienced Senior Clinical Research Physician to lead Phase I studies as Principal Investigator or Project Physician.

You'll work with our MHRA-accredited 100-bed unit, collaborating with nurses, pharmacy and wider clinical teams across early-phase studies, including healthy-volunteer populations, and contribute to safety oversight, data integrity and trial reporting.