Sante Publique à Espagne

France

Medical Devices and Consumer Healthcare

Permanent contract

The Toxicologist/Safety Expert is responsible for evaluating the safety and potential health risks of chemicals, pharmaceuticals, consumer products (nutrition and cosmetic), or environmental agents. This role involves review and evaluation of laboratory experiments, analyzing data, interpreting toxicological findings, writing toxicological reports and risk assessments on a variety of products while ensuring compliance with regulatory standards to protect public health.

The Toxicologist/Safety Expert is also involved in case management/vigilance management and post marketing surveillance.

• Design and evaluate toxicological studies (in vitro, in vivo, or computational).
• Ability to design and interpret studies under ISO 10993-1, including cytotoxicity, sensitization, irritation, and systemic toxicity.
• Assess the toxicological profile of substances including acute, chronic, reproductive, developmental, and genetic toxicity.
• Interpret toxicological data and prepare risk assessments.
• Prepare technical reports for regulatory submissions (EC mark for medical devices, Novel Food/Novel Ingredient)
• Collaborate with cross-functional teams including regulatory affairs, product development, and safety assessment.
• Stay updated on regulatory guidelines and scientific advancements in toxicology.
• Provide expert advice on hazard identification, exposure assessment, and risk characterization.

• Advanced degree (MSc or PhD) in Toxicology, Pharmacology, Biology, Biochemistry, or a related field.
• Strong knowledge of toxicological principles, testing methods, and regulatory frameworks.
• Experience with toxicological databases and modeling tools (e.g., QSAR, PBPK).
• English proficiency (French is a valuable asset).
• Excellent analytical, problem-solving, and communication skills.
• Familiarity with Good Laboratory Practice (GLP) and ethical standards in animal testing.

Preferred skills:

• Certification by a recognized toxicology board (e.g., DABT, ERT).
• Experience in regulatory toxicology, especially in pharmaceuticals, medical devices, cosmetics, or agrochemicals.
• Knowledge of alternative methods to animal testing (NAMs, in silico models).
• Proficiency in ISO 10993 standards for biological evaluation of medical devices.
• Proficiency in Novel Food Regulations and Food Safety Assessment (allergy, contaminants, human exposure).