Structural Biology Researcher: Fe-S Cluster Assembly

CEA; Grenoble; On-site; EUR 45,000 - 65,000; Full time

Benefits offered by this job

Canteen/meal vouchers

85% transport costs covered

Skill training to boost career

Job summary

The French Alternative Energies and Atomic Energy Commission (CEA) Grenoble site seeks a Researcher in Structural Biology to investigate the mechanisms of iron-sulfur cluster assembly. The role centers on structural characterization of protein complexes involved in Fe-S biogenesis and transport to a client protein crucial for cofactor biosynthesis.

The successful candidate will use cryo-EM and, where possible, X-ray crystallography to resolve molecular interactions during assembly, while

Qualifications

• Solid background in laboratory biochemistry including protein expression and purification.
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Responsibilities

• Carry out structural characterization of protein complexes involved in Fe-S cluster assembly and transport.
• Perform cryo-EM grid preparation, data processing, and structural model refinement; crystallography when possible.
• Establish protocols for producing protein samples for structural and spectroscopic analyses; collaborate across groups.

Job description

The French Alternative Energies and Atomic Energy Commission (CEA) Grenoble site seeks a Researcher in Structural Biology to investigate the mechanisms of iron-sulfur cluster assembly. The role centers on structural characterization of protein complexes involved in Fe-S biogenesis and transport to a client protein crucial for cofactor biosynthesis.

The successful candidate will use cryo-EM and, where possible, X-ray crystallography to resolve molecular interactions during assembly, while