Postdoc in Biochemistry: Metalloproteins & Fe-S Biogenesis

CNRS - National Center for Scientific Research

France

On-site

EUR 38,000 - 49,000

Full time

8 days ago

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Job summary

CNRS, Institut de Biologie Intégrative de la Cellule, located in Gif-sur-Yvette, France, invites applications for a post-doctoral fellow in Biochemistry/Biophysics. The project investigates Fe-S cluster biogenesis and its link to fatty acids synthesis, using in vitro reconstitutions of ISC machinery and multiple biophysical methods.

The successful candidate will purify proteins, reconstitute complexes under anaerobic conditions, and perform comprehensive biochemical and biophysical analyses.

Qualifications

  • PhD in biochemistry/biophysics or related field.
  • Strong background in protein purification and metallo-proteins.
  • Experience with spectroscopic methods (UV-Vis, CD, NMR).

Responsibilities

  • Purify proteins and reconstitute complexes under anaerobic conditions.
  • Carry out sample preparation and analyses using biochemical and biophysical techniques.
  • Collaborate within the Biochemistry of Metalloproteins and Associated Diseases team at I2BC (CNRS).

Skills

Protein purification
Metallo-proteins
Spectroscopy methods
Structural biology

Education

PhD in biochemistry/biophysics or related field

Tools

UV-Vis spectroscopy
Circular dichroism (CD)
Isothermal titration calorimetry (ITC)
Biolayer interferometry (BLI)
Mass spectrometry
NMR

Job description

CNRS, Institut de Biologie Intégrative de la Cellule, located in Gif-sur-Yvette, France, invites applications for a post-doctoral fellow in Biochemistry/Biophysics. The project investigates Fe-S cluster biogenesis and its link to fatty acids synthesis, using in vitro reconstitutions of ISC machinery and multiple biophysical methods.

The successful candidate will purify proteins, reconstitute complexes under anaerobic conditions, and perform comprehensive biochemical and biophysical analyses.

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