Research Engineer Process Development (F/M)

Institut Curie; France; Hybrid; EUR 65,000 - 85,000; Full time

Benefits offered by this job

Cutting-edge therapies

Dynamic environment

Competitive salary

Career development

Job summary

Institut Curie’s CellAction laboratory seeks a skilled professional to develop and optimize manufacturing processes for cell and gene therapies, including viral and non-viral vectors and genome editing. You will transfer pre-GMP processes to robust workflows, develop analytical methods, monitor CPPs and CQAs, and ensure GMP compliance while collaborating with multidisciplinary teams.

Join a dynamic, collaborative environment offering cutting-edge therapies, career development, and a competitive

Responsibilities

• Develop and optimize manufacturing processes for cell and gene therapies, including viral/non-viral vectors and genome editing.
• Transfer pre-GMP processes into robust, reproducible workflows suitable for clinical manufacturing.
• Develop analytical methods and monitor CPPs and CQAs to ensure product quality.
• Collaborate with multidisciplinary teams, contribute to troubleshooting, and support continuous process improvement.
• Prepare technical documentation and ensure compliance with GMP and regulatory requirements.
• Identify innovative approaches to improve process efficiency and maintain technology watch in the field of cell and gene therapy.

Job description

Laboratory - CellAction

CellAction is part of Institut Curie’s commitment to building unique expertise in cell and gene therapy. It integrates multidisciplinary competencies in bioinformatics, target discovery and validation, molecular biology, genome editing, viral and non-viral vector design, cell engineering, and the development of in vitro and in vivo tumor models for cell and gene therapy applications. Furthermore, CellAction provides pre-GMP process development expertise, aiming to generate fully characterized, GMP-ready cell therapy products that can be manufactured in dedicated GMP facilities and subsequently evaluated in clinical settings.

In 2025, CellAction was permanently established at the Saint-Cloud site of Institut Curie.

At the Process Development group at CellAction, our activities focus on the development and optimization of manufacturing processes for cell- and gene-based therapies, ensuring translational feasibility and compliance with regulatory standards for clinical-grade production.

https://curie.fr/cellaction-un-laboratoire-unique-pour-lacces-aux-therapies-cellulaires-et-geniques

Missions / Responsibilities

• Develop and optimize manufacturing processes for cell and gene therapies, including viral/non-viral vectors and genome editing.
• Transfer pre-GMP processes into robust, reproducible workflows suitable for clinical manufacturing.
• Develop analytical methods and monitor critical process parameters (CPPs) and critical quality attributes (CQAs) to ensure product quality.
• Collaborate with multidisciplinary teams, contribute to troubleshooting, and support continuous process improvement.
• Prepare technical documentation and ensure compliance with GMP and regulatory requirements.
• Identify innovative approaches to improve process efficiency and maintain technology watch in the field of cell and gene therapy.

What We Offer

• Opportunity to work on cutting-edge therapies
• Dynamic and collaborative environment
• Competitive salary and benefits package
• Career development opportunities